The Center, formerly named the Center for Human Genetics, was established in 2004. It combined two of Marshfield Clinic’s internationally known research assets: the Center for Medical Genetics, founded in 1994, and the Personalized Medicine Research Center, started in 2001.
The Center for Precision Medicine Research focuses its research on discovering the structure of the human genome and the hunt for genes that influence human health disorders. The discovery at Marshfield in 1989 of short tandem repeat polymorphisms revolutionized the study of human genetics, and Marshfield maps are among the most reliable and widely used maps of the human genome in the world.
The Personalized Medicine Research Project was a logical outgrowth of initial genomic research. If doctors can understand which genes and environmental factors are involved in a disease, they may be better able to target the disease with specific medications that affect these particular pathways. This information might also enable doctors to predict the risk of disease in an individual and prescribe preventive measures. In 2002, the Center for Precision Medicine Research launched what is now the largest population-based genetic research project in the United States, involving more than 20,000 central Wisconsin residents.
The Marshfield Clinic is one of four partners in the Wisconsin Genomics Initiative (WGI), a historic collaboration. The WGI vision is to be able to predict, for individual patients in a clinical setting, the risks of disease susceptibility and treatment response using the combined power of cutting edge genetic, phenotypic, and environmental analysis. Each of the four partners is a leader in one or more areas needed for a successful effort.
The mission of the Center for Precision Medicine Research is to conduct translational research in medical genetics that substantially improves patient care.
Dr. Murray Brilliant, the Interim Director of the Center for Precision Medicine Research, affirms that the Center is committed to advancing scientific knowledge through genetics research and to translating that knowledge into practical applications that will foster improved health.
PMRP Winter/Spring 2017 Newsletter
Learn about a survey that asked patients their views on sharing their genomic data for research, plans for biobank expansion, and how genetics research helps doctors prescribe medicine to patients.
PMRP Summer/Fall 2015 Newsletter
In this issue, we introduce you to the Precision Medicine Initiative, a new research program that will perform personalized medicine on a large scale.