Clinical Trials

Enrolling Trials

1-10  of  133
9177,Phase II Study of Dose-Adjusted EPOCH+/-Rituximab in Adults With Untreated Burkitt Lymphoma, c-MYC Positive Diffuse Large B-Cell Lymphoma and Plasmablastic Lymphoma
Bseiso, Ali W
Lymph Gland - Non-Hodgkin's
Adult
The primary objective is: To determine PFS, EFS and OS of risk adaptive DA-EPOCH-R in newly diagnosed Burkitt Lymphoma, c-MYC + DLBCL and DA-EPOCH in c-MYC+ plasmablastic lymphoma = 18 years. Secondary objectives are to: Assess predictive value of early FDG-PET/CT scans on PFS. Obtain pilot comparative molecular profiling of HIV negative and positive BL, c-MYC + DLBCL and c-MYC+ plasmablastic lymphoma. Assess the toxicity of risk adaptive DA-EPOCH-R in newly diagnosed Burkitt Lymphoma, c-MYC + DLBCL and DA-EPOCH in c-MYC+ plasmablastic lymphoma = 18 years.
Spindler, Marilyn K
(715) 387-9444
Diagnostic & Treatment Center
3401 CRANBERRY BLVD
WESTON, WI  54476
Lakeview Medical Center
1700 West Stout Street
Rice Lake, WI  54868
Marshfield Clinic At James Beck Cancer Center
2251 NORTH SHORE DR
RHINELANDER, WI  54501
Marshfield Clinic Cancer Care At St Michaels
900 ILLINOIS AVE
STEVENS POINT, WI  54481
Mfld Clinic Cancer Care at Sacred Heart Hospital
900 W CLAIREMONT AVE
EAU CLAIRE, WI  54701
Minocqua Center
9601 TOWNLINE RD
MINOCQUA, WI  54548
Rice Lake Center
1700 W STOUT ST
RICE LAKE, WI  54868
Sacred Heart Hospital (Eau Claire)
900 W Clairemont Ave
Eau Claire, WI  54701
St. Clare's (Weston)
3400 Ministry Parkway
Weston, WI  54476
St. Josephs Hospital - Marshfield
611 Saint Joseph Ave
Marshfield, WI  54449
St. Mary's
2251 North Shore Drive
Rhinelander, WI  54501
St. Michaels Hospital
900 Illinois Ave
Stevens Point, WI  54481
Weston Center
3501 CRANBERRY BLVD
WESTON, WI  54476
A Children's Oncology Group Protocol for Collecting and Banking Pediatric Research Specimens Including Rare Pediatric Tumors, No age restrictions
Mcmanus, Michael J
Biology
Child
This study is collecting and storing malignant, borderline malignant neoplasms, and related biological samples from young patients with cancer. Collecting and storing samples of tumor tissue, blood, and bone marrow from patients with cancer to study in the laboratory may help the study of cancer in the future.
Carpenter, Bonnie M
(715) 389-3639
Marshfield Clinic Research Foundation
1000 N Oak
Marshfield, WI  54449
St. Josephs Hospital - Marshfield
611 Saint Joseph Ave
Marshfield, WI  54449
A Children's Oncology Group Protocol for Collecting and Banking Relapsed Acute Lymphoblastic Leukemia Research Specimens
Mcmanus, Michael J
Biology
Child
The objectives of the study are to establish a mechanism to bank specimens to tumor cells and host germline DNA from patients with acute lymphoblastic leukemia (ALL) at first and subsequent relapse. To make these specimens available to qualified researchers to study the biology of ALL.
Carpenter, Bonnie M
(715) 389-3639
Marshfield Center
1000 N OAK AVE
MARSHFIELD, WI  54449
St. Josephs Hospital - Marshfield
611 Saint Joseph Ave
Marshfield, WI  54449
A Study Exploring Two Strategies of Rivaroxaban (JNJ39039039; BAY-59-7939) and One of Oral Vitamin K Antagonist in Patients With Atrial Fibrillation Who Undergo Percutaneous Coronary Intervention (PIONEER AF-PCI)
Srivastava, Rohit
Cardiology - Atrial Fibrillation
Adult
The purpose of the study is to determine if rivaroxaban or VKA in combination with other antiplatelet therapies is safe to use in patients with atrial fibrillation who also receive stents.
Pernsteiner-Mueller, Paula L
(715) 393-1335
Diagnostic & Treatment Center
3401 CRANBERRY BLVD
WESTON, WI  54476
St. Clare's (Weston)
3400 Ministry Parkway
Weston, WI  54476
Weston Center
3501 CRANBERRY BLVD
WESTON, WI  54476
A Study to Evaluate the Effect of Long-term Treatment With BELVIQ (Lorcaserin HCl) on the Incidence of Major Adverse Cardiovascular Events and Conversion to Type 2 Diabetes Mellitus in Obese and Overweight Subjects With Cardiovascular Disease or Multiple Cardiovascular Risk Factors (CAMELLIA-TIMI)
Rezkalla, Shereif H
Cardiology
Adult
The objective is to demonstrate that, in obese and overweight subjects with cardiovascular (CV) disease and/or multiple CV risk factors, lorcaserin HCI 10 mg administered twice daily does not increase the incidence of major adverse cardiovascular events myocardial infarction, or stroke, or CV death compared to placebo, with a noninferiority margin for the hazard ratio 1.2 To confirm that, in subjects without any type of diabetes at Baseline, lorcaserin HCI 10 mg BID reduces the incidence of conversion to type 2 diabetes mellitus compared to placebo.
Beck, Carol M
(715) 389-3144
St. Josephs Hospital - Marshfield
611 Saint Joseph Ave
Marshfield, WI  54449
A011202, A Randomized Phase III Trial Evaluating the Role of Axillary Lymph Node Dissection in Breast Cancer Patients (cT1-3 N1) Who Have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemotherapy
Wernberg, Jessica A
Breast - Breast
Adult
This randomized phase III trial studies lymph node dissection and radiation therapy to see how well it works compared to radiation therapy alone in treating patients with breast cancer previously treated with chemotherapy and surgery. Lymph node dissection may remove cancer cells that have spread to nearby lymph nodes in patients with breast cancer. Radiation therapy uses high-energy x-rays to kill tumor cells. It is not yet known if radiation therapy alone is as effective as lymph node dissection and radiation therapy together.
St. Josephs Hospital - Marshfield
611 Saint Joseph Ave
Marshfield, WI  54449
A021202, Prospective Randomized Phase II Trial of Pazopanib (NSC # 737754) Versus Placebo in Patients With Progressive Carcinoid Tumors
Islam, Rezwan
Stomach, Intestine, Gut - Rare (Gist, Neuroendocrine, Carcinoid, Anal Canal)
Adult
This randomized phase II trial studies how well pazopanib hydrochloride works in treating patients with carcinoid tumors that are growing, spreading, or getting worse. Pazopanib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Bulgrin, Angela M
(715) 221-7261
Petz, Judy A
(715) 221-7278
Chippewa Center
2655 CTY HWY I
CHIPPEWA FALLS, WI  54729
Eau Claire Center
2116 Craig Rd
Eau Claire, WI  54701
Lakeview Medical Center
1700 West Stout Street
Rice Lake, WI  54868
Marshfield Clinic At James Beck Cancer Center
2251 NORTH SHORE DR
RHINELANDER, WI  54501
Marshfield Clinic Cancer Care At St Michaels
900 ILLINOIS AVE
STEVENS POINT, WI  54481
Mfld Clinic Cancer Care at Sacred Heart Hospital
900 W CLAIREMONT AVE
EAU CLAIRE, WI  54701
Minocqua Center
9601 TOWNLINE RD
MINOCQUA, WI  54548
Rice Lake Center
1700 W STOUT ST
RICE LAKE, WI  54868
Sacred Heart Hospital (Eau Claire)
900 W Clairemont Ave
Eau Claire, WI  54701
St. Clare's (Weston)
3400 Ministry Parkway
Weston, WI  54476
St. Mary's
2251 North Shore Drive
Rhinelander, WI  54501
St. Michaels Hospital
900 Illinois Ave
Stevens Point, WI  54481
Wausau Center
2727 PLAZA DRIVE
WAUSAU, WI  54401
Weston Center
3501 CRANBERRY BLVD
WESTON, WI  54476
Wisconsin Rapids Center
220 24TH ST SOUTH
WISCONSIN RAPIDS, WI  54494
A031201, Phase III Trial of Enzalutamide Versus Enzalutamide, Abiraterone and Prednisone for Castration Resistant Metastatic Prostate Cancer
Fagbemi, Seth O
Bladder, Prostate, Kidney - Prostate
Adult
This randomized phase III trial studies enzalutamide to see how well it works compared to enzalutamide, abiraterone acetate, and prednisone in treating patients with castration-resistant metastatic prostate cancer. Androgens can cause the growth of prostate cancer cells. Drugs, such as enzalutamide, abiraterone acetate, and prednisone, may lessen the amount of androgens made by the body.
Bulgrin, Angela M
(715) 221-7261
Chippewa Center
2655 CTY HWY I
CHIPPEWA FALLS, WI  54729
Diagnostic & Treatment Center
3401 CRANBERRY BLVD
WESTON, WI  54476
Ladysmith Center
906 College Ave W
Ladysmith, WI  54848
Marshfield Clinic At James Beck Cancer Center
2251 NORTH SHORE DR
RHINELANDER, WI  54501
Marshfield Clinic Cancer Care At St Michaels
900 ILLINOIS AVE
STEVENS POINT, WI  54481
Mfld Clinic Cancer Care at Sacred Heart Hospital
900 W CLAIREMONT AVE
EAU CLAIRE, WI  54701
Minocqua Center
9601 TOWNLINE RD
MINOCQUA, WI  54548
Rice Lake Center
1700 W STOUT ST
RICE LAKE, WI  54868
Sacred Heart Hospital (Eau Claire)
900 W Clairemont Ave
Eau Claire, WI  54701
St. Clare's (Weston)
3400 Ministry Parkway
Weston, WI  54476
St. Josephs Hospital - Marshfield
611 Saint Joseph Ave
Marshfield, WI  54449
St. Mary's
2251 North Shore Drive
Rhinelander, WI  54501
St. Michaels Hospital
900 Illinois Ave
Stevens Point, WI  54481
Wausau Center
2727 PLAZA DRIVE
WAUSAU, WI  54401
Weston Center
3501 CRANBERRY BLVD
WESTON, WI  54476
Wisconsin Rapids Center
220 24TH ST SOUTH
WISCONSIN RAPIDS, WI  54494
A041202, A Randomized Phase III Study of Bendamustine Plus Rituximab Versus Ibrutinib Plus Rituximab Versus Ibrutinib Alone in Untreated Older Patients (>/= 65 Years of Age) with Chronic Lymphocytic Leukemia (CLL)
Bseiso, Ali W
Blood - CLL - Chronic Lymphocyctic
Adult
This randomized phase III trial studies rituximab with bendamustine hydrochloride or ibrutinib to see how well they work compared to ibrutinib alone in treating older patients with previously untreated chronic lymphocytic leukemia. Monoclonal antibodies, such as rituximab, can block cancer growth in difference ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. Drugs used in chemotherapy, such as bendamustine hydrochloride, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Ibrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. It is not yet know whether rituximab with bendamustine hydrochloride is more effective than rituximab and ibrutinib or ibrutinib alone in treating chronic lymphocytic leukemia.
Chippewa Center
2655 CTY HWY I
CHIPPEWA FALLS, WI  54729
Diagnostic & Treatment Center
3401 CRANBERRY BLVD
WESTON, WI  54476
Ladysmith Center
906 College Ave W
Ladysmith, WI  54848
Marshfield Clinic At James Beck Cancer Center
2251 NORTH SHORE DR
RHINELANDER, WI  54501
Marshfield Clinic Cancer Care At St Michaels
900 ILLINOIS AVE
STEVENS POINT, WI  54481
Mfld Clinic Cancer Care at Sacred Heart Hospital
900 W CLAIREMONT AVE
EAU CLAIRE, WI  54701
Minocqua Center
9601 TOWNLINE RD
MINOCQUA, WI  54548
Rice Lake Center
1700 W STOUT ST
RICE LAKE, WI  54868
Sacred Heart Hospital (Eau Claire)
900 W Clairemont Ave
Eau Claire, WI  54701
St. Clare's (Weston)
3400 Ministry Parkway
Weston, WI  54476
St. Josephs Hospital - Marshfield
611 Saint Joseph Ave
Marshfield, WI  54449
St. Mary's
2251 North Shore Drive
Rhinelander, WI  54501
St. Michaels Hospital
900 Illinois Ave
Stevens Point, WI  54481
Wausau Center
2727 PLAZA DRIVE
WAUSAU, WI  54401
Weston Center
3501 CRANBERRY BLVD
WESTON, WI  54476
A081105, Randomized Double Blind Placebo Controlled Study of Erlotinib or Placebo in Patients With Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC)
Onitilo, Adedayo A
Lung - Lung
Adult
This randomized phase III trial studies how well erlotinib hydrochloride compared to placebo works in treating patients with stage IB-IIIA non-small cell lung cancer that has been completely removed by surgery. Erlotinib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Bulgrin, Angela M
(715) 221-7261