• Peggy Peissig Ph.D., M.B.A.

  • Director of BIRC

    • Center for Human Genetics
    • 1000 North Oak Ave. ML8 Marshfield, WI 54449


Ph.D., Clinical Investigation, University of Wisconsin , Madison
M.B.A. , University of Wisconsin , Eau Claire
B.S., University of Wisconsin , River Falls

Work Experience

2016 to Present:
Research Scientist, Biomedical Informatics Research Center, Marshfield, WI
2015 to Present:
Chief Research Informatics Officer, Biomedical Informatics Research Center, Marshfield Clinic Research Foundation , Marshfield, WI
2015 to Present:
Director of Biomedical Informatics Research Center, Biomedical Informatics Research Center, Marshfield Clinic Research Foundation , Marshfield, WI
2014 to 2016:
Associate Research Scientist, Biomedical Informatics Research Center, Marshfield Clinic Research Foundation, Marshfield, WI
2014 to 2015:
Interim Director of Biomedical Informatics Research Center , Biomedical Informatics Research Center, Marshfield Clinic Research Foundation , Marshfield, WI
2013 to 2014:
Associate Research Scientist, Center for Human Genetics, Marshfield Clinic Research Foundation, Marshfield, WI
2011 to 2013:
Director, Health Informatics, Security Health Plan, Marshfield, WI
2005 to 2013:
Researcher, Biomedical Informatics Research Center, Marshfield Clinic Research Foundation , Marshfield, WI
2005 to 2011:
Associate Director , Biomedical Informatics Research Center, Marshfield Clinic Research Foundation , Marshfield, WI
1997 to 2008:
Director of Informatics and Decision Support , Information Systems, Marshfield Clinic, Marshfield, WI
1990 to 1997:
Research Database Manager/Database Analyst , Epidemiology and Biostatistics, Marshfield Medical Research Foundation , Marshfield, WI
1988 to 1990:
Management Information Systems Lecturer, University of Wisconsin , Eau Claire, WI


Dr. Peggy Peissig, PhD is an Associate Research Scientist with 25 years of experience in health care and research informatics. Her primary research areas include electronic health record (EHR) phenotyping, pharmaco genetics and adverse drug event prediction and surveillance. She holds the John Melski Endowed Distinguished Scientist Chair for Biomedical Informatics at the Marshfield Clinic where she is the Chief Research Informatics Officer and Director of the Biomedical Informatics Research Center. She led the informatics effort when developing the Personalized Medicine Research Project (PMRP). PMRP consists of 20,000+ individuals with long-term (30 year average) nearly complete electronic health records combined with a biobank of DNA, plasma and serum samples. She also led the EHR phenotyping core for the Wisconsin Genome Initiative, a collaboration in translational research, between Marshfield Clinic, UW-Madison and the Medical College of Wisconsin. Dr. Peissig is a past co-chair of the Phenotyping Workgroup for the eMERGE (Electronic Medical Records and Genomics) Network.

Research Interests

Areas of research interest include translational medicine involving the integration of genomic information into the electronic health record (EHR), EHR-based phenotyping, clinical informatics and the application of machine learning to health care-related problems.

Select Publications

  • DeStefano F, Eaker ED, Broste SK, Nordstrom DL, Peissig PL, Vierkant RA, Konitzer KA, Gruber RL, Layde PM. Epidemiologic research in an integrated regional medical care system: the Marshfield Epidemiologic Study Area. J Clin Epidemiol. 1996 Jun;49(6):643-52.
    PubMed ID: 8656225
  • Sirohi E, Peissig PL. Study of effect of drug lexicons on medication extraction from electronic medical records. Pac Symp Biocomput. 2005 Mar; ::308-318.
    PubMed ID: 15759636
  • Wilke RA, Berg RL, Peissig PL, Kitchner TE, Sijercic B, McCarty CA, McCarty DJ. Use of an electronic medical record for the identification of research subjects with diabetes mellitus. Clin Med Res. 2007 Mar;5(1):1-7.
    PubMed ID: 17456828
  • Peissig PL, Christensen CA, Melski JW, Starren JB. Making the paperless transition: Marshfield Clinic's Cattails EHR. AMIA Annu Symp Proc. 2007 Oct;11 :1200.
    PubMed ID: 18694289
  • Peissig PL, Sirohi E, Berg RL, Brown-switzer C, Ghebranious N, McCarty CA, Wilke RA. Construction of atorvastatin dose-response relationships using data from a large population-based DNA biobank. Basic Clin Pharmacol Toxicol. 2007 Apr;100(4):286-288.
    PubMed ID: 17371534
  • McCarty CA, Peissig PL, Caldwell MD, Wilke RA. The Marshfield Clinic Personalized Medicine Research Project: 2008 scientific update and lessons learned in the first 6 years. Personalized Medicine. 2008 Sep;5(5):529-542.
  • Oberg R, Rasmussen LV, Melski JW, Peissig PL, Starren JB. Evaluation of the google search appliance for patient cohort discovery. AMIA Annu Symp Proc. 2008 Nov; :1104.
    PubMed ID: 18999072
  • Konitzer KA, Praxel TA, Peissig PL, Berger NR, Turnquist CM. Enabling Quality of Care Metric Reporting Using an EMR. Clin Med Res. 2008 Dec;6(3/4):150,PS2-33.
  • Wesbrook SD, Giampietro PF, Glurich IE, McCarty CA, Peissig PL, Starren JB, Uphoff TS, Zaleski CA, Vidaillet HJ. Marshfield Clinic, Marshfield Wisconsin/ Community Based Approaches to Personalized Health Care: Marshfield Clinic Personalized Health Care: Pioneers, Partnerships, Progress. 2008 Nov; :231-42.
  • Wilke R, Berg RL, Linneman JG, Peissig PL, Starren J, Ritchie MD, McCarty CA. Quantification of the clinical modifiers impacting high-density lipoprotein cholesterol in the community: Personalized Medicine Research Project. Prev Cardiol. 2010;13(2):63-8.
    PubMed ID: 20377807
  • Berg B, Peissig PL, Page D, Vidaillet HJ. Relational Rule-Learning on High-dimensional Medical Data, in Neural and Information Processing Systems (NIPS). Workshop on Predictive Models for Personalized Medicine. Neural Information Processing Systems Foundation.. 2010 Dec;
  • Weiss J, Berg B, Peissig PL, McCarty CA, Page D. Clustering Overly-Specific Features in Electronic Medical Records, in Neural and Information Processing Systems (NIPS). Workshop on Predictive Models for Personalized Medicine. Neural Information Processing Systems Foundation.. 2010 Dec;
  • Schildcrout JD, Basford MA, Pulley JM, Masys DR, Roden DM, Wang D, Chute CG, Kullo IJ, Carrell D, Peissig PL, Kho A, Denny JC. An analytical approach to characterize morbidity profile dissimilarity between distinct cohorts using electronic medical records. J Biomed Inform. 2010 Dec;43(6):914-23.
    PubMed ID: 20688191
  • Huser V, Peissig PL, Christensen CA, Starren JB. Evaluation of Commercial Workflow Engine for Modeling Clinical Processes in Quality Improvement and Decision Support. Clinical Medicine & Research. 2010 Mar;8(1):46.
  • Waudby CJ, Berg RL, Linneman JG, Rasmussen LV, Peissig PL, Chen L, McCarty CA. Cataract research using electronic health records. BMC Ophthalmology. 2011 Nov;11(32)
    PubMed ID: 22078460
  • Denny JC, Crawford D, Ritchie MD, Bielinski S, Basford MA, Bradford Y, Chai H, Bastarache L, Zuvich R, Peissig PL, Carrell D, Ramirez A, Pathak J, Wilke R, Rasmussen LV, Wang X, Pacheco J, Kho A, Hayes M, Weston N, Matsumoto M, Kopp P, Newton KM, Jarvik G, Li R, Manolio T, Kullo IJ, Chute CG, Chisholm R, Larson EB, McCarty CA, Masys DR, Roden DM, De Andrade M. Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies. AMERICAN JOURNAL OF HUMAN GENETICS. 2011 Oct;89(4):529-42.
    PubMed ID: 21981779
  • Turner SD, Berg RL, Linneman JG, Peissig PL, Crawford DC, Denny JC, Roden DM, McCarty CA, Ritchie MD, Wilke RA. Knowledge-driven multi-locus analysis reveals gene-gene interactions influencing HDL cholesterol level in two independent EMR-linked biobanks. PLoS One. 2011 May;6(5):e19586.
    PubMed ID: 21589926
  • Conway M, Berg RL, Carrell D, Denny JC, Kho AN, Kullo IJ, Linneman JG, Pacheco JA, Peissig P, Rasmussen L, Weston N, Chute CG, Pathak J. Analyzing the heterogeneity and complexity of Electronic Health Record oriented phenotyping algorithms. AMIA Annu Symp Proc. 2011;2011 :274-83.
    PubMed ID: 22195079
  • Kho AN, Pacheco JA, Peissig PL, Rasmussen L, Newton KM, Weston N, Crane PK, Pathak J, Chute CG, Bielinski SJ, Kullo IJ, Li R, Manolio TA, Chisholm RL, Denny JC. Electronic medical records for genetic research: results of the eMERGE consortium. Sci Transl Med. 2011 Apr 20;3(79):79re1.
    PubMed ID: 21508311
  • McCarty CA, Chisholm RL, Chute CG, Kullo IJ, Jarvik GP, Larson EB, Li R, Masys DR, Ritchie MD, Roden DM, Struewing JP, Wolf WA, Peissig P. The eMERGE Network: a consortium of biorepositories linked to electronic medical records data for conducting genomic studies. BMC Med Genomics. 2011 Jan 26;4 :13.
    PubMed ID: 21269473
  • Liu J, Peissig PL, Zhang C, Burnside E, McCarty CA, Page D. High-Dimensional Structured Feature Screening Using Binary Markov Random Fields. JMLR Workshop Conf Proc. 2012;22 :712-721.
    PubMed ID: 23606924
  • Weiss JC, Natarajan S, Peissig PL, McCarty CA, Page D. Machine Learning for Personalized Medicine: Predicting Primary Myocardial Infarction from Electronic Health Records. AI Magazine. 2012 Dec;33(4):33.
  • Duellman T, Warren CL, Peissig PL, Wynn M, Yang J. Matrix metalloproteinase-9 genotype as a potential genetic marker for abdominal aortic aneurysm. Circ Cardiovasc Genet.. 2012 Oct;5(5):529-37.
    PubMed ID: 22942228
  • thompson W, Rasmussen LV, Pacheco J, Peissig PL, Denny JC, Kho A, Miller AW, Pathak J. An evaluation of the NQF Quality Data Model for representing Electronic Health Record driven phenotyping algorithms. AMIA Annu Symp Proc.. 2012 Nov;2012 :911-20.
    PubMed ID: 23304366
  • Weiss JC, Natarajan S, Peissig PL, McCarty CA, Page D. Statistical Relational Learning to Predict Primary Myocardial Infarction from Electronic Health records. Innovative Applications of Artificial Intelligence (IAAI). 2012;2012
  • Liu J, Zhang C, McCarty CA, Peissig PL, Burnside E, Page D. Graphical-model Based Multiple Testing under Dependence, with Applications to Genome-wide Association Studies. Proceedings of the 28th Conference on Uncertainty in Artificial Intelligence (UAI). 2012;2012
  • Kawaler E, Cobian A, Peissig PL, Cross DS, Yale SH, Craven M. Learning to Predict Post-Hospitalization VTE Risk from EHR Data. AMIA Annu Symp Proc. 2012;2012 :436-45.
    PubMed ID: 23304314
  • Page D, Costa V, Natarajan S, Barnard A, Peissig PL, Caldwell MD. Identifying Adverse Drug Events by Relational Learning Association for the Advancement of Artificial Intelligence. 2012; :15999-1605.
  • Davis J, Costa V, Peissig PL, Caldwell MD, Berg E, Page D. Demand-Driven Clustering in Relational Domains for Predicting Adverse Drug Events Proceedings of the 29th International Conference on Machine Learning. 2012;
  • Rasmussen LV, Peissig PL, McCarty CA, Starren JB. Development of an optical character recognition pipeline for handwritten form fields from an electronic health record. J Am Med Inform Assoc. 2012 Jun;19(e1):e90-e95.
    PubMed ID: 21890871
  • Peissig PL, Rasmussen LV, Berg RL, Linneman JG, McCarty CA, Waudby CJ, Chen L, Denny JC, Wilke R, Pathak J, Carrell D, Kho A, Starren JB. Importance of multi-modal approaches to effectively identify cataract cases from electronic health records. JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION. 2012 Mar;19(2):225-34.
    PubMed ID: 22319176
  • Kho A, Hayes M, Rasmussen-Torvik L, Pacheco J, Thompson WK, Armstrong L, Denny JC, Peissig PL, Miller AW, Wei W, Bielinski S, Chute CG, Leibson C, Jarvik G, Crosslin D, Carlson C, Newton KM, Wolf W, Chisholm R, Lowe W. Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study. JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION. 2012 Mar;19(2):212-8.
    PubMed ID: 22101970
  • Weiss JC, Page D, Peissig PL, Natarajan S, McCarty C. Statistical Relational Learning to Predict Primary Myocardial Infarction from Electronic Health Records. Proc Innov Appl Artif Intell Conf. 2012;2012 :2341-2347.
    PubMed ID: 25360347
  • Liu J, Page D, Nassif H, Peissig PL, McCarty CA, Onitilo AA, Burnside E. Genetic variants improve breast cancer risk prediction on mammograms. AMIA Annu Symp Proc. 2013 Nov;2013(eCollection 2013):876-85.
    PubMed ID: 24551380
  • Davis JG, Santos Costa V, Peissig PL, Caldwell MD, Page D. A preliminary investigation into predictive models for adverse drug events. Expanding the Boundaries of Health Informations Using Artificial Intelligence: Papers from the AAAI . 2013 Jan; :8-11.
  • Gottesman O, Kuivaniemi H, Tromp G, Faucett W, Li R, Manolio T, Sanderson S, Kannry J, Zinberg R, Basford M, Brilliant MH, Carey D, Chisholm R, Chute CG, Connolly J, Crosslin D, Denny J, Gallego C, Haines J, Hakonarson H, Harley J, Jarvik G, Kohane I, Kullo IJ, Larson EB, McCarty C, Ritchie MD, Roden DM, Smith M, Bottinger E, Williams M, The eMerge Network, Peissig P. The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future. GENETICS IN MEDICINE. 2013 Oct;15(10):761-71.
    PubMed ID: 23743551
  • Kho A, Rasmussen LV, Connolly J, Peissig PL, Starren J, Hakonarson H, Hayes M. Practical challenges in integrating genomic data into the electronic health record. GENETICS IN MEDICINE. 2013 Oct;15(10):772-8.
    PubMed ID: 24071798
  • Newton KM, Peissig PL, Kho A, Bielinski S, Berg RL, Choudhary V, Basford M, Chute CG, Kullo IJ, Li R, Pacheco J, Rasmussen LV, Spangler L, Denny J. Validation of electronic medical record-based phenotyping algorithms: results and lessons learned from the eMERGE network. JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION. 2013 Jun;20(e1):e147-54.
    PubMed ID: 23531748
  • Denny J, Bastarache L, Ritchie MD, Carroll R, Zink R, Mosley J, Field J, Pulley JM, Ramirez A, Bowton E, Basford M, Carrell D, Peissig PL, Kho A, Pacheco J, Rasmussen LV, Crosslin D, Crane P, Pathak J, Bielinski S, Pendergrass S, Xu H, Hindorff L, Li R, Manolio T, Chute CG, Chisholm R, Larson EB, Jarvik G, Brilliant MH, McCarty CA, Kullo IJ, Haines J, Crawford D, Masys DR, Roden DM. Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data. NATURE BIOTECHNOLOGY. 2013 Nov;31(12):1102-1111.
    PubMed ID: 24270849
  • McDavid A, Crane P, Newton KM, Crosslin D, McCormick W, Weston N, Ehrlich K, Hart E, Harrison R, Kukull WA, Rottscheit CM, Peissig PL, Stefanski EL, McCarty CA, Zuvich R, Ritchie MD, Haines J, Denny J, Schellenberg GD, De Andrade M, Kullo I, Li R, Mirel D, Crenshaw A, Bowen J, Li G, Tsuang D, McCurry S, Teri L, Larson EB, Jarvik G, Carlson C. Enhancing the power of genetic association studies through the use of silver standard cases derived from electronic medical records. PLoS One. 2013 Jun;8(6):e63481.
    PubMed ID: 23762230
  • Hall M, Dudek S, Goodloe R, Crawford D, Pendergrass S, Peissig PL, Brilliant MH, McCarty CA, Ritchie MD. Environment-wide association study (ewas) for type 2 diabetes in the marshfield personalized medicine research project biobank. Pac Symp Biocomput. 2014;19 :200-11.
    PubMed ID: 24297547
  • Peissig PL, Santos Costa V, Caldwell MD, Rottscheit CM, Berg RL, Mendonca EA, Page D. Relational machine learning for electronic health record-driven phenotyping. J Biomed Inform. 2014 Dec;52 :260-70.
    PubMed ID: 25048351
  • Muthalagu A, Pacheco J, Aufox S, Peissig PL, Fuehrer J, Tromp G, Kho A, Rasmussen-Torvik L. A Rigorous Algorithm To Detect And Clean Inaccurate Adult Height Records Within EHR Systems. Appl Clin Inform. 2014 Feb;5(1):118-26.
    PubMed ID: 24734128
  • Liu J, Peissig PL, McCarty CA, Onitilo AA, Trentham-Dietz A, Burnside E. New genetic variants improve personalized breast cancer diagnosis. AMIA Jt Summits Transl Sci Proc.. 2014 Apr;eCollection 2014 :83-9.
    PubMed ID: 25717406
  • Wei W, Feng Q, Jiang L, Waitara M, Iwuchukwu O, Roden D, Jiang M, Xu H, Krauss RM, Rotter JI, Nickerson DA, Davis R, Berg RL, Peissig PL, McCarty CA, Wilke R, Denny J. Characterization of Statin Dose Response in Electronic Medical Records. CLINICAL PHARMACOLOGY & THERAPEUTICS. 2014 Mar;95(3):331-8.
    PubMed ID: 24096969
  • Shameer K, Denny J, Ding K, Jouni H, Crosslin D, De Andrade M, Chute CG, Peissig PL, Pacheco J, Li R, Bastarache L, Kho A, Ritchie MD, Masys DR, Chisholm R, Larson EB, McCarty CA, Roden DM, Jarvik G, Kullo IJ. A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects. HUMAN GENETICS. 2014 Jan;133(1):95-109.
    PubMed ID: 24026423
  • Rasmussen LV, Thompson WK, Pacheco J, Kho A, Carrell D, Pathak J, Peissig PL, Tromp G, Denny J, Starren JB. Design patterns for the development of electronic health record-driven phenotype extraction algorithms. JOURNAL OF BIOMEDICAL INFORMATICS. 2014 Oct;51 :280-6.
    PubMed ID: 24960203
  • Malinowski JR, Denny JC, Bielinski SJ, Basford MA, Bradford Y, Peissig PL, Carrell D, Crosslin DR, Pathak J, Rasmussen L, Pacheco J, Kho A, Newton KM, Li R, Kullo IJ, Chute CG, Chisholm RL, Jarvik GP, Larson EB, McCarty CA, Masys DR, Roden DM, de Andrade M, Ritchie MD, Crawford DC. Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network. PLoS One. 2014 Dec;9(12):e111301.
    PubMed ID: 25436638
  • Ritchie MD, Verma SS, Hall MA, Goodloe RJ, Berg RL, Carrell DS, Carlson CS, Chen L, Crosslin DR, Denny JC, Jarvik G, Li R, Linneman JG, Pathak J, Peissig P, Rasmussen LV, Ramirez AH, Wang X, Wilke RA, Wolf WA, Torstenson ES, Turner SD, McCarty CA. Electronic medical records and genomics (eMERGE) network exploration in cataract: several new potential susceptibility loci. Mol Vis. 2014 Sep;20 :1281-95.
    PubMed ID: 25352737
  • Cronin RM, Field JR, Bradford Y, Shaffer CM, Carroll RJ, Mosley JD, Bastarache L, Edwards TL, Hebbring SJ, Lin S, Hindorff LA, Crane PK, Pendergrass SA, Ritchie MD, Crawford DC, Pathak J, Bielinski SJ, Carrell DS, Crosslin DR, Ledbetter DH, Carey DJ, Tromp G, Williams MS, Larson EB, Jarvik GP, Peissig PL, Brilliant MH, McCarty CA, Chute CG, Kullo IJ, Bottinger E, Chisholm R, Smith ME, Roden DM, Denny JC. Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index. Front Genet. 2014 Aug 5;5 :250.
    PubMed ID: 25177340
  • Ng MC, Shriner D, Chen BH, Li J, Chen WM, Guo X, Liu J, Bielinski SJ, Yanek LR, Nalls MA, Comeau ME, Rasmussen-Torvik LJ, Jensen RA, Evans DS, Sun YV, An P, Patel SR, Lu Y, Long J, Armstrong LL, Wagenknecht L, Yang L, Snively BM, Palmer ND, Mudgal P, Langefeld CD, Keene KL, Freedman BI, Mychaleckyj JC, Nayak U, Raffel LJ, Goodarzi MO, Chen YD, Taylor HA, Correa A, Sims M, Couper D, Pankow JS, Boerwinkle E, Adeyemo A, Doumatey A, Chen G, Mathias RA, Vaidya D, Singleton AB, Zonderman AB, Igo RP, Sedor JR, Kabagambe EK, Siscovick DS, McKnight B, Rice K, Liu Y, Hsueh WC, Zhao W, Bielak LF, Kraja A, Province MA, Bottinger EP, Gottesman O, Cai Q, Zheng W, Blot WJ, Lowe WL, Pacheco JA, Crawford DC, Grundberg E, Rich SS, Hayes MG, Shu XO, Loos RJ, Borecki IB, Peyser PA, Cummings SR, Psaty BM, Fornage M, Iyengar SK, Evans MK, Becker DM, Kao WH, Wilson JG, Rotter JI, Sale MM, Liu S, Rotimi CN, Bowden DW, Peissig P. Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes. PLoS Genet.. 2014 Aug 7;10(8):e1004517.
    PubMed ID: 25102180
  • Wu Y, Liu J, Page D, Peissig P, McCarty C, Onitilo AA, Burnside ES. Comparing the value of mammographic features and genetic variants in breast cancer risk prediction. AMIA Annu Symp Proc. 2014 Nov 14;2014 :1228-37.
    PubMed ID: 25954434
  • Nadkarni GN, Gottesman O, Linneman JG, Chase H, Berg RL, Farouk S, Nadukuru R, Lotay V, Ellis S, Hripcsak G, Peissig P, Weng C, Bottinger EP. Development and validation of an electronic phenotyping algorithm for chronic kidney disease. AMIA Annu Symp Proc. 2014 Nov 14;2014 :907-16.
    PubMed ID: 25954398
  • Schrodi SJ, Debarber A, He M, Ye Z, Peissig PL, VanWormer JJ, Haws RM., Brilliant MH, Steiner R. Prevalence estimation for monogenic autosomal recessive diseases using population-based genetic data. Hum Genet. 2015 Jun;134(6):659-69.
    PubMed ID: 25893794
  • He M, Person TN, Hebbring S, Heinzen E, Ye Z, Schrodi SJ, McPherson EW, Lin S, Peissig PL, Brilliant MH, O'Rawe J, Robinson RJ, Lyon GJ, Wang K. SeqHBase: a big data toolset for family based sequencing data analysis. JOURNAL OF MEDICAL GENETICS. 2015 Apr;52(4):282-8.
    PubMed ID: 25587064
  • Bielinski SJ, Pathak J, Carrell DS, Takahashi PY, Olson JE, Larson NB, Liu H, Sohn S, Wells QS, Denny JC, Rasmussen-Torvik LJ, Pacheco JA, Jackson KL, Lesnick TG, Gullerud RE, Decker PA, Pereira NL, Ryu E, Dart RA, Peissig P, Linneman JG, Jarvik GP, Larson EB, Bock JA, Tromp GC, de Andrade M, Roger VL. A Robust e-Epidemiology Tool in Phenotyping Heart Failure with Differentiation for Preserved and Reduced Ejection Fraction: the Electronic Medical Records and Genomics (eMERGE) Network. J Cardiovasc Transl Res. 2015 Aug 21;8 :475-83.
    PubMed ID: 26195183
  • Shirts BH, Salama JS, Aronson SJ, Chung WK, Gray SW, Hindorff LA, Jarvik GP, Plon SE, Stoffel EM, Tarczy-Hornoch PZ, Van Allen EM, Weck KE, Chute CG, Freimuth RR, Grundmeier RW, Hartzler AL, Li R, Peissig PL, Peterson JF, Rasmussen LV, Starren JB, Williams MS, Overby CL. CSER and eMERGE: current and potential state of the display of genetic information in the electronic health record. J Am Med Inform Assoc. 2015 Nov 3;22(6):1231-42..
    PubMed ID: 26142422
  • Interleukin 1 Genetics Consortium:, Peissig, P. Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis. Lancet Diabetes Endocrinol. 2015 Apr;3(4):243-53.
    PubMed ID: 25726324
  • Crosslin DR, Carrell DS, Burt A, Kim DS, Underwood JG, Hanna DS, Comstock BA, Baldwin E, de Andrade M, Kullo IJ, Tromp G, Kuivaniemi H, Borthwick KM, McCarty CA, Peissig PL, Doheny KF, Pugh E, Kho A, Pacheco J, Hayes MG, Ritchie MD, Verma SS, Armstrong G, Stallings S, Denny JC, Carroll RJ, Crawford DC, Crane PK, Mukherjee S, Bottinger E, Li R, Keating B, Mirel DB, Carlson CS, Harley JB, Larson EB, Jarvik GP. Genetic variation in the HLA region is associated with susceptibility to herpes zoster. Genes Immun. 2015 Jan;16(1):1-7.
    PubMed ID: 25297839
  • Peissig PL, Nikolai A, Glurich I, Brilliant M. Drug Discover and Evaluation: Pharmacological Assays. Personalized Medicine. 2015 Mar 20; :1-16.
  • Mo H, Thompson WK, Rasmussen LV, Pacheco JA, Jiang G, Kiefer R, Zhu Q, Xu J, Montague E, Carrell DS, Lingren T, Mentch FD, Ni Y, Wehbe FH, Peissig PL, Tromp G, Larson EB, Chute CG, Pathak J, Denny JC, Speltz P, Kho AN, Jarvik GP, Bejan CA, Williams MS, Borthwick K, Kitchner TE, Roden DM, Harris PA. Desiderata for computable representations of electronic health records-driven phenotype algorithms. J Am Med Inform Assoc. 2015 Nov 5;22(6):1220-30..
    PubMed ID: 26342218
  • Liu J, Wu Y, Ong I, Page D, Peissig P, McCarty C, Onitilo AA, Burnside E. Leveraging Interaction between Genetic Variants and Mammographic Findings for Personalized Breast Cancer Diagnosis. AMIA Jt Summits Transl Sci Proc.. 2015 Mar 25;2015 :107-11.
    PubMed ID: 26306250
  • Herr TM, Bielinski SJ, Bottinger E, Brautbar A, Brilliant M, Chute CG, Denny J, Freimuth RR, Hartzler A, Kannry J, Kohane IS, Kullo IJ, Lin S, Pathak J, Peissig P, Pulley J, Ralston J, Rasmussen L, Roden D, Tromp G, Williams MS, Starren J. A conceptual model for translating omic data into clinical action. J Pathol Inform. 2015 Aug;6 :46.
    PubMed ID: 26430534
  • Namjou B, Marsolo K, Lingren T, Ritchie MD, Verma SS, Cobb BL, Perry C, Kitchner TE, Brilliant MH, Peissig PL, Borthwick KM, Williams MS, Grafton J, Jarvik GP, Holm IA, Harley JB. A GWAS Study on Liver Function Test Using eMERGE Network Participants. PLoS One. 2015 Sep 28;10(9):e0138677.
    PubMed ID: 26413716
  • Wu Y, Abbey CK, Chen X, Liu J, Page DC, Alagoz O, Peissig P, Onitilo AA, Burnside ES. Developing a utility decision framework to evaluate predictive models in breast cancer risk estimation. Journal of Medical Imaging. 2015 Aug 17;2(4):041005.
  • Herr TM, Bielinski SJ, Bottinger E, Brautbar A, Brilliant M, Chute CG, Cobb BL, Denny JC, Hakonarson H, Hartzler AL, Hripcsak G, Kannry J, Kohane IS, Kullo IJ, Lin S, Manzi S, Marsolo K, Overby CL, Pathak J, Peissig P, Pulley J, Ralston J, Rasmussen L, Roden DM, Tromp G, Uphoff T, Weng C, Wolf W, Williams MS, Starren J. Practical considerations in genomic decision support: The eMERGE experience. J Pathol Inform. 2015 Sep 28;6 :50.
    PubMed ID: 26605115
  • Natarajan S, Peissig PL, Page D. Relational Learning for Sustainable Health. Computational Sustainability. 645. Switzerland, Springer International Publishing, 2016
  • Heatherly R, Rasmussen LV, Peissig PL, Pacheco JA, Harris P, Denny JC, Malin BA. A multi-institution evaluation of clinical profile anonymization. J Am Med Inform Assoc. 2016 Apr 13;23(e1):e131-7..
    PubMed ID: 26567325
  • Burnside ES, Liu J, Wu Y, Onitilo AA, McCarty CA, Page CD, Peissig PL, Trentham-Dietz A, Kitchner T, Fan J, Yuan M. Comparing Mammography Abnormality Features to Genetic Variants in the Prediction of Breast Cancer in Women Recommended for Breast Biopsy. Acad Radiol. 2016 Jan 26;23(1):62-9.
    PubMed ID: 26514439
  • Kim D, Lucas A, Glessner J, Verma SS, Bradford Y, Li R, Frase AT, Hakonarson H, Peissig P, Brilliant M, Ritchie MD. BIOFILTER AS A FUNCTIONAL ANNOTATION PIPELINE FOR COMMON AND RARE COPY NUMBER BURDEN. Pac Symp Biocomput. 2016 Feb;21 :357-68.
    PubMed ID: 26776200
    PubMed ID: 26776191