• James Donahue DVM, PhD, MPH

  • Epidemiologist - Senior

    • Center for Clinical Epidemiology & Population Health
    • 1000 North Oak Ave. ML2 Marshfield, WI 54449


BS, Biology, University of Minnesota, Saint Paul
DVM, Zoonotic Diseases, University of Minnesota, Saint Paul
MPH, Infectious Diseases, Harvard University School of Public Health, Boston
1985 to 1988:
Epidemiology Fellow at FDA and NCI, National Institutes of Health, Washington
PhD, Epidemiology, Johns Hopkins School of Hygiene and Public Health, Baltimore

Work Experience

1985 to 1987:
Epidemiology Fellow, USPHS Epidemiology Training Program, Epidemiology and Clinical Toxicology Unit, Center for Food Safety and Nutrition, Food and Drug Administration, Washington
1987 to 1988:
Guest Scientist, Environmental Epidemiology Branch, Division of Cancer Etiology, National Cancer Institute, Bethesda
1988 to 1989:
Postdoctoral Position, Cancer Training Grant, National Cancer Institute and the Johns Hopkins School of Hygiene and Public Health, Baltimore
1988 to 1992:
Project Director, Frequency of Agents Communicated by Transfusion Study and the Hepatitis C After Transfusion Study, The Johns Hopkins School of Hygiene and Public Health, Baltimore
1992 to 2000:
Instructor in Medicine, Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston
2000 to 2003:
Area Epidemiologist, Veterinary Services, Animal and Plant Health Inspection Service, United States Department of Agriculture, Madison
2003 to Present:
Epidemiologist, Marshfield Clinic Research Institute, Marshfield


Dr. Donahue is an epidemiologist with experience in infectious disease epidemiology and pharmacoepidemiology. He joined CCEPH in 2003 and is currently an investigator in the Vaccine Safety Datalink, a project in which Marshfield Clinic and several other medical care organizations received funding from CDC to investigate the safety of licensed vaccines using a large linked database. His current projects include studies of influenza vaccine safety during pregnancy and the safety of the 9-valent human papilloma virus vaccine.

Research Interests

Vaccine safety
Infectious disease epidemiology
Study design methodology

Select Publications

  • Klein NP, Lewis E, McDonald J, Fireman B, Naleway A, Glanz J, Jackson LA, Donahue JG, Jacobsen SJ, Weintraub E, Baxter R. Risk factors and familial clustering for fever 7-10days after the first dose of measles vaccines. VACCINE. 2017 Mar 14;35(12):1615-1621.
    PubMed ID: 28233624
  • Donahue JG, Kieke BA, King JP, DeStefano F, Mascola MA, Irving SA, Cheetham TC, Glanz JM, Jackson LA, Klein NP, Naleway AL, Weintraub E, Belongia EA. Association of spontaneous abortion with receipt of inactivated influenza vaccine containing H1N1pdm09 in 2010-11 and 2011-12. VACCINE. 2017 Sep 25;35(40):5314-5322.
    PubMed ID: 28917295
  • Szilagyi PG, Blumkin A, Treanor JJ, Gallivan S, Albertin C, Lofthus GK, Schnabel KC, Donahue JG, Thompson MG, Shay DK. Incidence and viral aetiologies of acute respiratory illnesses (ARIs) in the United States: a population-based study. Epidemiol Infect.. 2016 Jul;144(10):2077-2086.
    PubMed ID: 26931351
  • Naleway AL, Crane B, Smith N, Daley MF, Donahue J, Gee J, Greene SK, Harrington T, Jackson LA, Klein NP, Tseng HF, Vellozzi C, Weintraub ES. Absence of venous thromboembolism risk following quadrivalent human papillomavirus vaccination, Vaccine Safety Datalink, 2008-2011. VACCINE. 2016 Jan 2;34(1):167-71.
    PubMed ID: 26549361
  • Cheetham TC, Marcy SM, Tseng HF, Sy LS, Liu IL, Bixler F, Baxter R, Donahue JG, Naleway AL, Jacobsen SJ. Risk of Herpes Zoster and Disseminated Varicella Zoster in Patients Taking Immunosuppressant Drugs at the Time of Zoster Vaccination. Mayo Clin Proc. 2015 Jul;90(7):865-73.
    PubMed ID: 26051268
  • Donahue JG, Kieke BA, Szilagy PG, Blumkin AK, Hilgemann DJ, Flanders WD, Shay DK, Meece JK, Treanor JJ, Belongia EA. Can the rolling cross-sectional survey design be used to estimate the effectiveness of influenza vaccines? VACCINE. 2014 Oct;32(48):6440-4.
    PubMed ID: 25284810
  • Glanz JM, Newcomer S, Narwaney K, Hambidge SJ, Daley MF, Wagner N, McClure D, Xu S, Rowhani-Rahbar A, Lee GM, Nelson JC, Donahue JG, Naleway AL, Nordin JD, Lugg M, Weintraub ES. A population-based cohort study of undervaccination in 8 managed care organizations across the United States. JAMA Pediatr. 2013 Mar;167(3):274-81.
    PubMed ID: 23338829
  • McCarthy NL, Weintraub E, Vellozzi C, Duffy J, Gee J, Donahue JG, Jackson M, Lee GM, Glanz J, Baxter R, Lugg M, Naleway A, Omer S, Nakasato C, Vazquez-Benitez G, DeStefano F. Mortality Rates and Cause-of-Death Patterns in a Vaccinated Population AMERICAN JOURNAL OF PREVENTIVE MEDICINE. 2013;45(1):91-97.
  • Tseng H, Sy L, Qian L, Marcy SM, Jackson LA, Glanz J, Nordin J, Baxter R, Naleway AL, Donahue JG, Weintraub E, Jacobsen SJ, Vaccine Safety Datalink Team. Safety of a Tetanus-Diphtheria-Acellular Pertussis Vaccine When Used Off-Label in an Elderly Population. CLINICAL INFECTIOUS DISEASES. 2013 Feb;56(3):315-321.
    PubMed ID: 23196953
  • Irving SA, Kieke BA, Donahue JG, Mascola MA, Baggs J, DeStefano F, Cheetham T, Jackson L, Naleway AL, Glanz J, Nordin JD, Belongia EA, for the Vaccine Safety Datalink. Trivalent Inactivated Influenza Vaccine and Spontaneous Abortion. OBSTETRICS AND GYNECOLOGY. 2013 Jan;121(1):159-165.
    PubMed ID: 23262941
  • Jackson LA, Peterson D, Nelson JC, Marcy SM, Naleway AL, Nordin JD, Donahue JG, Hambidge SJ, Balsbaugh C, Baxter R, Marsh T, Madziwa L, Weintraub E. Vaccination Site and Risk of Local Reactions in Children 1 Through 6 Years of Age. PEDIATRICS. 2013 Feb;131(2):283-9.
    PubMed ID: 23319538
  • Tseng H, Sy L, Liu I, Qian L, Marcy SM, Weintraub E, Yih K, Baxter R, Glanz JM, Donahue JG, Naleway A, Nordin J, Jacobsen SJ. Postlicensure surveillance for pre-specified adverse events following the 13-valent pneumococcal conjugate vaccine in children. VACCINE. 2013 May;31(22):2578-83.
    PubMed ID: 23579258
  • McCarthy NL, Irving SA, Donahue JG, Weintraub E, Gee J, Belongia EA, Baggs J. Vaccination coverage levels among children enrolled in the Vaccine Safety Datalink. VACCINE. 2013 Dec;31(49):5822-6.
    PubMed ID: 24135576
  • Hechter R, Qian L, Sy L, Greene SK, Weintraub ES, Naleway AL, Rowhani-Rahbar A, Donahue JG, Daley MF, Vazquez-Benitez G, Lugg M, Jacobsen SJ. Secular trends in diagnostic code density in electronic healthcare data from health care systems in the Vaccine Safety Datalink Project. VACCINE. 2013 Feb;31(7):1080-5.
    PubMed ID: 23267842
  • Irving SA, Patel DC, Kieke BA, Donahue JG, Vandermause MF, Shay DK, Belongia EA. Comparison of clinical features and outcomes of medically attended influenza A and influenza B in a defined population over four seasons: 2004-2005 through 2007-2008. Influenza Other Respi Viruses. 2012 Jan;6(1):37-43.
    PubMed ID: 21668663
  • Donahue JG, Coleman LA, Bender J, Kempf DL, Vandermause MF, McGraw PJ, Lauer DC, Belongia EA. Prospective Study of Avian Influenza Infection in Backyard Poultry Flocks and Flock Handlers in Wisconsin. Vector Borne Zoonotic Dis. 2011 Sep;11(9):1293-7.
    PubMed ID: 21612537
  • Belongia EA, Kieke BA, Donahue JG, Coleman LA, Irving SA, Meece JK, Vandermause MF, Lindstrom S, Garguillo P, Shay DK. Influenza vaccine effectiveness in Wisconsin during the 2007-08 season: Comparison of interim and final results. VACCINE. 2011 Jul;29(38):6558-63.
    PubMed ID: 21767593
  • McCarthy NL, Gee J, Weintraub E, Donahue JG, Nordin JD, Daley MF, Naleway AL, Henninger M, Baxter R, Crane B, Aukes L, Wagner N, Fisher S, Jacobsen SJ, Sy L, Baggs J. Monitoring vaccine safety using the Vaccine Safety Datalink: Utilizing immunization registries for pandemic influenza. VACCINE. 2011 Jul;29(31):4891-6.
    PubMed ID: 21596088
  • Donahue JG, Kieke BA, Gargiullo PM, Jumaan AO, Berger NR, Mccauley JS, Belongia EA. Herpes Zoster and Exposure to the Varicella Zoster Virus in an Era of Varicella Vaccination. AMERICAN JOURNAL OF PUBLIC HEALTH. 2010 Jun;100(6):1116-22.
    PubMed ID: 20075320
  • Belongia EA, Kieke BA, Donahue JG, Greenlee RT, Balish A, Foust A, Lindstrom S, Shay DK, Marshfield Influenza Study Group. Effectiveness of inactivated influenza vaccines varied substantially with antigenic match from the 2004-2005 season to the 2006-2007 season. J Infect Dis. 2009 Jan;199(2):159-67.
    PubMed ID: 19086915
  • Donahue JG, Kieke BA, Yih WK, Berger NR, Mccauley JS, Baggs J, Zangwill KM, Baxter R, Eriksen E, Glanz JM, Hambidge SJ, Klein NP, Lewis EM, Marcy SM, Naleway AL, Nordin J, Ray P, Belongia EA, Vaccine Safety Datalink Team. Varicella vaccination and ischemic stroke in children: is there an association? PEDIATRICS. 2009 Feb;123(2):e228-34.
    PubMed ID: 19171574
  • Irving SA, Donahue JG, Shay DK, Ellis-Coyle TL, Belongia EA. Evaluation of self-reported and registry-based influenza vaccination status in a Wisconsin cohort. VACCINE. 2009 Nov;27(47):6546-9.
    PubMed ID: 19729083
  • Naleway AL, Belongia EA, Donahue JG, Kieke BA, Glanz JM, Vaccine Safety Datalink Team. Risk of immune hemolytic anemia in children following immunization. VACCINE. 2009 Dec;27(52):7394-7.
    PubMed ID: 19766577
  • Mullooly JP, Donahue JG, DeStefano F, Baggs J, Eriksen E, VSD Data Quality Working Group. Predictive value of ICD-9-CM codes used in vaccine safety research. Methods Inf Med. 2008;47(4):328-35.
    PubMed ID: 18690366
  • Belongia EA, Coleman LA, Donahue JG. Effectiveness of Influenza Vaccination. N Engl J Med. 2007 Dec;357(26):2728; author reply 2730-1.
    PubMed ID: 18160695
  • Cohen ND, Donahue JG, Carey VJ, Seahorn JL, Piercy D, Donahoe JK, Williams DM, Brown SE, Riddle TW. Case-control study of early-term abortions (early fetal losses) associated with mare reproductive loss syndrome in central Kentucky. J Am Vet Med Assoc. 2003 Jan;222(2):210-217.
    PubMed ID: 12555985
  • Donahue JG, Chan KA, Andrade SE, Beck A, Boles M, Buist DS, Carey VJ, Chandler JM, Chase GA, Ettinger B, Fischman P, Goodman MF, Guess HA, Gurwitz JH, LaCroix AZ, Levin TR, Platt R. Gastric and duodenal safety of daily alendronate. Arch Intern Med. 2002 Apr;162(8):936-942.
    PubMed ID: 11966346
  • Andrade SE, Gurwitz JH, Chan KA, Donahue JG, Beck A, Boles M, Buist DA, Goodman MF, LaCroix AZ, Levin TR, Platt R. Validation of diagnoses of peptic ulcers and bleeding from administrative databases: a multi-health maintenance organization study. J Clin Epidemiol. 2002 Mar;55(3):310-313.
    PubMed ID: 11864803
  • Kaye KS, Sands K, Donahue JG, Chan KA, Fishman P, Platt R. Preoperative drug dispensing as predictor of surgical site infection. Emerg Infect Dis. 2001 Jan;7(1):57-65.
    PubMed ID: 11266295
  • Donahue JG, Fuhlbrigge AL, Finkelstein JA, Fagan J, Livingston JM, Lozano P, Platt R, Weiss ST, Weiss KB. Asthma pharmacotherapy and utilization by children in 3 managed care organizations. The Pediatric Asthma Care Patient Outcomes Research Team. J Allergy Clin Immunol. 2000 Dec;106(6):1108-1114.
    PubMed ID: 11112894
  • Chan KA, Andrade SE, Boles M, Buist DA, Chase GA, Donahue JG, Goodman MF, Gurwitz JH, LaCroix AZ, Platt R. Inhibitors of hydroxymethylglutaryl-coenzyme A reductase and risk of fracture among older women. Lancet. 2000 Jun;355(9222):2185-2188.
    PubMed ID: 10881890
  • Donahue JG, Greineder DK, Connor-Lacke L, Canning CF, Platt R. Utilization and cost of immunotherapy for allergic asthma and rhinitis. Ann Allergy Asthma Immunol. 1999 Apr;82(4):339-347.
    PubMed ID: 10227332
  • Donahue JG, Andrade SE, Cain EM, DeFor TA, Goodman MF, Gurwitz JH, Platt R. Lamotrigine and severe skin eruptions. Pharmacoepidemiol Drug Saf. 1998 Nov;7(6):415-417.
    PubMed ID: 15073972
  • Donahue JG, Weiss ST, Livingston JM, Goetsch MA, Greineder DK, Platt R. Inhaled steroids and the risk of hospitalization for asthma. JAMA. 1997 Mar;277(11):887-891.
    PubMed ID: 9062326
  • Choo PW, Donahue JG, Platt R. Ibuprofen and skin and soft tissue superinfections in children with varicella. Ann Epidemiol. 1997 Oct;7(7):440-445.
    PubMed ID: 9349910
  • Donahue JG, Weiss ST, Goetsch MA, Livingston JM, Greineder DK, Platt R. Assessment of asthma using automated and full-text medical records. J Asthma. 1997;34(4):273-281.
    PubMed ID: 9250251
  • Donahue JG, Choo PW, Manson JE, Platt R. The incidence of herpes zoster. Arch Intern Med. 1995 Aug;155(15):1605-1609.
    PubMed ID: 7618983
  • Donahue JG, Munoz A, Ness PM, Brown DE, Yawn DH, McAllister HA, Reitz BA, Nelson KE. The declining risk of post-transfusion hepatitis C virus infection. N Engl J Med. 1992 Aug;327(6):369-373.
    PubMed ID: 1320736
  • Donahue JG, Nelson KE, Munoz A, Vlahov D, Rennie LL, Taylor EL, Saah AJ, Cohn S, Odaka NJ, Farzadegan H. Antibody to hepatitis C virus among cardiac surgery patients, homosexual men, and intravenous drug users in Baltimore, Maryland. Am J Epidemiol. 1991 Nov;134(10):1206-1211.
    PubMed ID: 1720924
  • Donahue JG, Nelson KE, Munoz A, McAllister HA, Yawn DH, Cohen ND. Transmission of HIV by transfusion of screened blood. N Engl J Med. 1990 Dec;323(24):1709.
    PubMed ID: 2233972
  • Donahue JG, Piesman J, Spielman A. Reservoir competence of white-footed mice for Lyme disease spirochetes. Am J Trop Med Hyg. 1987 Jan;36(1):92-96.
    PubMed ID: 3812887