• Shereif Rezkalla

  • Physician - Cardiology-Interventional


    • Cardiology
    • 1000 North Oak Ave. 2D2 Marshfield, WI 54449

Education


1989:
Interventional Cardiology, Wayne State University - Hospitals, Detroit
1988:
Cardiology, Wayne State University - Hospitals, Detroit
1985:
Internal Medicine, Wayne State University - Hospitals, Detroit
1982:
Rotating, St. John Macomb Hospital, Warren
1980:
Department of Internal Medicine & Surgery, El Mabarra Hospital, Assuit, Egypt
1976:
Flexible, Assuit University Affiliated Hospitals, Assuit, Egypt
1974:
MD, MBBCH, Assuit University Medical School, Assuit, Egypt

Work Experience


2000 to Present:
Clinical Professor of Medicine, University of Wisconsin, Madison
1994 to Present:
Cardiologist, Sacred Heart Hospital, Tomahawk
1993 to Present:
Director of Cardiovascular Research, Department of Cardiology, Marshfield Clinic, Marshfield
1991 to Present:
Cardiologist, Riverview Hospital, Wisconsin Rapids
1989 to Present:
Staff Cardiologist, Ministry St. Joseph's Hospital, Marshfield
1989 to Present:
Interventional Cardiologist, Marshfield Clinic, Marshfield
1995 to 2000:
Clinical Associate Professor of Medicine, University of Wisconsin, Madison
1989 to 1995:
Assistant Clinical Professor of Medicine, University of Wisconsin, Madison
1976 to 1978:
Director, Dewena and El Balayza Health Unit, Assuit, Egypt

Select Publications


  • Rezkalla SH, Khatib G. Diffuse eosinophlic gastroenteritis with normal endoscopic examination. Department of Medicine Bulletin. 1985;1 :29-31.
  • Rezkalla SH, Khatib G, Khatib R. Coxsackievirus B3 murine myocarditis: deleterious effects of nonsteroidal anti-inflammatory agents. J Lab Clin Med. 1986 Apr;107(4):393-395.
    PubMed ID: 2420912
  • Turi ZG, Rezkalla SH, Campbell CA, Kloner RA.. Amelioration of ischemia during angioplasty of the left anterior descending coronary artery with an autoperfusion catheter. Am J Cardiol. 1988 Sep;62(9):513-517.
    PubMed ID: 2970787
  • Rezkalla SH, Kloner RA., Khatib G, Smith F, Khatib R. Effect of metoprolol in acute coxsackievirus B3 murine myocarditis. J Am Coll Cardiol. 1988 Aug;12(2):412-414.
    PubMed ID: 2839568
  • Rezkalla SH, Kloner RA., Sowers J, Khatib R. Atrial natriuretic peptide in acute coxsackievirus murine myocarditis. Am J Cardiol. 1988 Jun;61(15):1361-1362.
    PubMed ID: 2837075
  • Rezkalla SH, Khatib R, Khatib G, Smith F, Walsh M, Sowers J, Kloner RA.. Effect of indomethacin in the late phase of coxsackievirus myocarditis in a murine model. J Lab Clin Med. 1988 Jul;112(1):118-121.
    PubMed ID: 2839587
  • Rezkalla SH, Moushmoush B, Connors BC, Turi ZG. Monitoring of ischemia during percutaneous coronary angioplasty: influence of guidewire, balloon placement, and lead selection. Cathet Cardiovasc Diagn. 1988;15(4):233-236.
    PubMed ID: 2976305
  • Turi ZG, Rezkalla SH, Campbell CA, Kloner RA.. Coronary angioplasty in patients with proximal epicardial stenosis. Results of a study of the autoperfusion balloon catheter in humans. Am J Cardiol. 1988;62 :513-517.
  • Rezkalla SH, Kloner RA., Khaw BA, Haber E, Fallon JT, Smith F, Khatib R. Detection of experimental myocarditis by monoclonal antimyosin antibody, Fab fragment. Am Heart J. 1989 Feb;117(2):391-395.
    PubMed ID: 2916411
  • Rezkalla SH, Kloner RA.. Management strategies in viral myocarditis. Am Heart J. 1989 Mar;117(3):706-708.
    PubMed ID: 2645754
  • Rezkalla SH, Kloner RA., Ensley J, al-Sarraf M, Revels S, Olivenstein A, Bhasin S, Kerpel-Fronious S, Turi ZG. Continuous ambulatory ECG monitoring during fluorouracil therapy: a prospective study. J Clin Oncol. 1989 Apr;7(4):509-514.
    PubMed ID: 2466960
  • Campbell CA, Rezkalla SH, Kloner RA., Turi ZG. The autoperfusion balloon angioplasty catheter limits myocardial ischemia and necrosis during prolonged balloon inflation. J Am Coll Cardiol. 1989 Oct;14(4):1045-1050.
    PubMed ID: 2794265
  • Campbell CA, Rezkalla SH, Kloner RA., Turi ZG. Electrocardiographic findings: regional myocardial blood flow and infarct size during 90 minute inflation of autoperfusion catheter. J Am Coll Cardiol. 1989;14 :1045-1050.
  • Hale S, Alker K, Rezkalla SH, Figures G, Kloner RA.. Adverse effects of cocaine on cardiovascular dynamics, myocardial blood flow, and coronary artery diameter in an experimental model. Am Heart J. 1989 Nov;118(5 Pt 1):927-933.
    PubMed ID: 2816705
  • Rezkalla SH, Turi ZG, Keedy D, Precevski P, Kloner RA.. Left main coronary angioplasty in a sheep model using a new left main autoperfusion balloon catheter. J Invasive Cardiology. 1989;1 :199-205.
  • Rezkalla SH, Boden WE, Kloner RA.. Identification and management of patients at risk for myocardial infarction extension. Practical Cardiology. 1989;15 :50-59.
  • Rezkalla SH, Kloner RA.. Author's reply. Management strategies in viral myocarditis. AMERICAN HEART JOURNAL. 1989 Dec;118(6):1355.
  • Rezkalla SH, Hale S, Kloner RA.. Cocaine-induced heart diseases. Am Heart J. 1990 Dec;120(6 Pt 1):1403-1408.
    PubMed ID: 2248185
  • Rezkalla SH, Kloner RA., Khatib G, Khatib R. Beneficial effects of captopril in acute coxsackievirus B3 murine myocarditis. CIRCULATION. 1990 Mar;81(3):1039-1046.
    PubMed ID: 2155071
  • Khatib R, Reyes MP, Smith F, Khatib G, Rezkalla SH. Enhancement of coxsackievirus B4 virulence by indomethacin. J Lab Clin Med. 1990 Jul;116(1):116-120.
    PubMed ID: 1695914
  • Rezkalla SH, Kloner RA., Khatib G, Khatib R. Effect of delayed captopril therapy on left ventricular mass and myonecrosis during acute coxsackievirus murine myocarditis. Am Heart J. 1990 Dec;120(6 Pt 1):1377-1381.
    PubMed ID: 2174203
  • Turi ZG, Rezkalla SH, Campbell CA, Kloner RA.. Left main percutaneous transluminal coronary angioplasty with the autoperfusion catheter in an animal model. Cathet Cardiovasc Diagn. 1990 Sep;21(1):45-50.
    PubMed ID: 2208267
  • Rezkalla SH, Kloner RA., Khatib G, Khatib R. Author's reply. Beneficial effects of captopril in acute coxsackievirus B3 murine myocarditis. CIRCULATION. 1990 Nov;82(5):1882-1883.
  • Hale S, Alker K, Rezkalla SH, Eisenhauer AC, Kloner RA.. Nifedipine protects the heart from the acute deleterious effects of cocaine if administered before but not after cocaine. CIRCULATION. 1991 Apr;83(4):1437-1443.
    PubMed ID: 2013159
  • Rezkalla SH, Kloner RA.. Cardiomyopathy. Cardiovascular Reviews & Reports. 1991;12 :53-66.
  • Rezkalla SH, Kloner RA.. Myocarditis. Cardiovascular Reviews & Reports. 1991;12 :48-53.
  • Rezkalla SH, Kloner RA.. Cocaine and vascular thrombosis. Cardiovascular Reviews & Reports. 1991;13 :54-57.
  • Rezkalla SH, Reinhart R. Author's reply. Starting aspirin therapy after operation. CIRCULATION. 1991 Aug;84(2):520-526.
  • Rezkalla SH, Reinhart RA. Starting aspirin therapy after operation. CIRCULATION. 1992 Apr;85(4):1637.
    PubMed ID: 1555306
  • Kloner RA., Hale S, Alker K, Rezkalla SH. The effects of acute and chronic cocaine use on the heart. CIRCULATION. 1992 Feb;85(2):407-419.
    PubMed ID: 1346509
  • Khatib R, Reyes MP, Khatib G, Smith F, Rezkalla SH, Kloner RA.. Focal ventricular thinning caused by indomethacin in the late phase of coxsackievirus B4 murine myocarditis. Am J Med Sci. 1992 Feb;303(2):95-98.
    PubMed ID: 1311498
  • Alam S, Rezkalla SH, Farkas P, Turi ZG. Deleterious cardiac effects of captopril during acute myocardial ischaemia in the dog. Cardiovasc Res. 1992 Mar;26(3):232-236.
    PubMed ID: 1423417
  • Groden DL, Zhang KQi, Rezkalla SH. Abnormal calcium tansients and contractile dynamics in rat myocytes exposed to cocaine. J Am Col Cardiology. 1992;19(Suppl A):194A.
  • Wolschleger KG, Rezkalla SH. Excimer laser coronary angioplasty. Marshfield Clinic Bulletin. 1992;28 :1-5.
  • Rezkalla SH, Hale S, Alker K, Kloner RA.. Flow-function dissociation following an acute dose of cocaine: effect of captopril on coronary flow. Coron Artery Dis. 1993 Mar;4(3):271-276.
    PubMed ID: 8269221
  • Rezkalla SH, Mazza JJ, Kloner RA., Tillema VB, Chang S. Effects of cocaine on human platelets in healthy subjects. Am J Cardiol. 1993 Jul;72(2):243-246.
    PubMed ID: 8328397
  • Raikar S, Rezkalla SH. Takayasu's arteritis: a report of three cases. Wis Med J. 1994 Jun;93(6):261-263.
    PubMed ID: 7915864
  • Rezkalla SH, Raikar S, Kloner RA.. Treatment of viral myocarditis with focus on captopril. Am J Cardiol. 1996 Mar;77(8):634-637.
    PubMed ID: 8610616
  • Rezkalla SH. The effect of digoxin on mortality and morbidity in patients with heart failure. The Digitalis Investigation Group. N Engl J Med. 1997 Feb;336(8):525-533.
    PubMed ID: 9036306
  • Rezkalla SH. Randomised double-blind trial of fixed low-dose warfarin with aspirin after myocardial infarction. Coumadin Aspirin Reinfarction Study (CARS) Investigators. Lancet. 1997 Aug;350(9075):389-396.
    PubMed ID: 9259652
  • Rezkalla SH, Kloner RA.. Substance abuse and athletes: a cardiovascular nightmare. American Journal of Medicine & Sports. 1999;1 :113-120.
  • Rezkalla SH, Kloner RA.. No-reflow phenomenon. CIRCULATION. 2002 Feb;105(5):656-662.
    PubMed ID: 11827935
  • Rezkalla SH, Mesa JE, Sharma PP, Kloner RA.. Myocardial infarction temporally related to ephedra -- a possible role for the coronary microcirculation. WMJ. 2002 Jul;101(7):64-66.
    PubMed ID: 12426924
  • Rezkalla SH, Kloner RA.. No-reflow phenomenon. Response. CIRCULATION. 2002 Nov;106(20):143e.
    PubMed ID: 12427665
  • Pfeffer MA, McMurray JJV, Velazquez EJ, Rouleau JL, Kober L, Maggioni AP, Solomon SD, Swedberg K, Van de Werf F, White H, Leimberger JD, Henis M, Edwards S, Zelenkofske S, Sellers MAnn, Califf RM, The Valsartan in Acute Myocardial Infarction Trial Investigators, including, Rezkalla SH. Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med. 2003 Nov;349(20):1893-1906.
    PubMed ID: 14610160
  • Rezkalla SH, Hayes JJ, Curtis BR, Aster RH. Eptifibatide-induced acute profound thrombocytopenia presenting as refractory hypotension. Catheter Cardiovasc Interv. 2003 Jan;58(1):76-79.
    PubMed ID: 12508202
  • Rezkalla SH, Sharma PP, Kloner RA.. Coronary no-flow and ventricular tachycardia associated with habitual marijuana use. Ann Emerg Med. 2003 Sep;42(3):365-369.
    PubMed ID: 12944889
  • Rezkalla SH. Successful direct stenting guided by intravascular ultrasound without contrast in a patient with renal dysfunction. J Interv Cardiol. 2003 Oct;16(5):449-453.
    PubMed ID: 14603803
  • Rezkalla SH. Contrast nephropathy. Clin Med Res. 2003 Oct;1(4):301-304.
    PubMed ID: 15931323
  • Rezkalla SH, Benz MA. Antiplatelet therapy from clinical trials to clinical practice. Clin Med Res. 2003;1(2):101-104.
    PubMed ID: 15931295
  • Artang R, Jurgensen GW, Frandsen NJ, Abildgaard U, Nielsen JDalsgaard, Rezkalla SH. Abciximab upregulates the number of glycoprotein IIb/IIIa receptors in vivo. J Am Coll Cardiol. 2003;41 :78A.
  • Kloner RA., Rezkalla SH. Cocaine and the heart. N Engl J Med. 2003 Feb;348(6):487-488.
    PubMed ID: 12571254
  • Rezkalla SH, Benz MA. Effectiveness of acetylcysteine on preventing renal dysfunction in patients undergoing coronary procedures. WMJ. 2004 Apr;103(1):38-41.
    PubMed ID: 15101466
  • Cannon CP, Braunwald E, McCabe CH, Rader DJ, Rouleau JL, Belder R, Joyal SV, Hill KA, Pfeffer MA, Skene AM, The Pravastatin or Atorvastatin Evaluation and Infection Therapy -- Thrombolysis in Myocardial Infarction 22 (PROVE IT -- TIMI 22) Study Group, including, Rezkalla SH, Kieffer EC. Intensive versus moderate lipid lowering with statins after acute coronary syndromes. New Engl J Med. 2004 Apr;350(15):1495-1504.
    PubMed ID: 15007110
  • Kloner RA., Rezkalla SH. Cardiac protection during acute myocardial infarction: where do we stand in 2004? J Am Coll Cardiol. 2004 Jul;44(2):276-286.
    PubMed ID: 15261919
  • Rezkalla SH, Kloner RA.. Ischemic preconditioning and pre-infarction angina in the clinical arena. Nature Clin Practice Cardiovasc Med. 2004 Dec;1(2):96-102.
  • Rezkalla SH, Kloner RA.. Preconditioning and the human heart. Panminerva Med. 2005 Jun;47(2):69-73.
    PubMed ID: 16210991
  • Ridker PM, Cannon CP, Morrow D, Rifai N, Rose LM, McCabe CH, Pfeffer MA, Braunwald E, The Pravastatin or Atorvastatin Evaluation and Infection Therapy -- Thrombolysis in Myocardial Infarction 22 (PROVE IT -- TIMI 22) Study Group, including, Rezkalla SH. C-reactive protein levels and outcomes after statin therapy. N Engl J Med. 2005 Jan;352(1):20-28.
    PubMed ID: 15635109
  • Bardy GH, Lee KL, Mark DB, Poole JE, Packer DL, Boineau R, Domanski M, Troutman C, Anderson J, Johnson G, McNulty SE, Clapp-Channing N, Davidson-Ray LD, Fraulo ES, Fishbein DP, Luceri RM, Ip JH, the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) Investigators, including, Hayes JJ, Rezkalla SH, Maassen KA. Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. N Engl J Med. 2005 Jan;352(3):225-237.
    PubMed ID: 15659722
  • Rezkalla SH, Kloner RA.. Coronary no-reflow phenomenon. Curr Treat Options Cardiovasc Med. 2005 May;7(1):75-80.
    PubMed ID: 15913506
  • Rezkalla SH, Kloner RA.. Ischemic preconditioning for the clinician Wis Med J. 2006 Jun;105(4):22-26.
  • Rezkalla SH, Holmes DR.. Lipid-rich plaque masquerading as a coronary thrombus. Clin Med Res. 2006 Jun;4(2):119-122.
    PubMed ID: 16809404
  • Vats HS, Hocking WG, Rezkalla SH. Suspected clopidogrel resistance in a patient with acute stent thrombosis. Nat Clin Pract Cardiovasc Med. 2006 Apr;3(4):226-230.
    PubMed ID: 16568132
  • Kloner RA., Rezkalla SH. Preconditioning, postconditioning and their application to clinical cardiology. Cardiovasc Res. 2006 May;70(2):297-307.
    PubMed ID: 16516180
  • Rezkalla SH, Kloner RA.. Cocaine-induced acute myocardial infarction. Clin Med Res. 2007 Sep;5(3):172-176.
    PubMed ID: 18056026
  • Rezkalla SH, Kloner RA.. Preconditioning in humans. Heart Fail Rev. 2007 Dec;12(3-4):201-206.
    PubMed ID: 17508280
  • Ghebranious N, Giampietro PF, Wesbrook FP, Rezkalla SH. A novel microdeletion at 16p11.2 harbors candidate genes for aortic valve development, seizure disorder, and mild mental retardation. Am J Med Genet A. 2007 Jun;143A(13):1462-1471.
    PubMed ID: 17568417
  • Rezkalla SH, Ahmed M. Management strategies for ST-elevation myocardial infarction in the emergency department. WMJ. 2007 Jul;106(4):219-224.
  • Kloner RA., Rezkalla SH. To drink or not to drink? That is the question. CIRCULATION. 2007 Sep;116(11):1306-1317.
    PubMed ID: 17846344
  • Rezkalla SH, Kloner RA.. Coronary no-reflow phenomenon: From the experimental laboratory to the cardiac catheterization laboratory. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS. 2008 Dec;72(7):950-957.
    PubMed ID: 19021281
  • Rezkalla SH. To drink or not to drink? That is the question. CIRCULATION. 2008 Feb;117(6):e159; author reply e160.
    PubMed ID: 17846344
  • Schwartz GG, Olsson AG, Ballantyne CM, Barter PJ, Holme IM, Kallend D, Leiter LA, Leitersdorf E, McMurray JJV, Shah PK, Tardif JC, Chaitman B, Duttinger-Maddux R, Mathieson J, dal-OUTCOMES Committees and Investigators., Rezkalla SH. Rationale and design of the dal-OUTCOMES trial: efficacy and safety of dalcetrapib in patients with recent acute coronary syndrome. AMERICAN HEART JOURNAL. 2009 Dec;158(6):896-901.e3.
  • Schwartz BG, Rezkalla SH, Kloner RA.. Cardiovascular effects of cocaine. CIRCULATION. 2010 Dec;122(24):2558-69.
    PubMed ID: 21156654
  • Rezkalla SH, Kloner RA.. Influenza-related Viral Myocarditis in the Era of H1N1 WMJ. 2010 Aug;109(4):23-7.
  • Rezkalla SH, Dharmashankar KC, Abdalrahman IB, Kloner RA.. No-Reflow Phenomenon Following Percutaneous Coronary Intervention for Acute Myocardial Infarction: Incidence, Outcome, and Effect of Pharmacologic Therapy. J Interv Cardiol. 2010 Oct;23(5):429-36.
    PubMed ID: 20819117
  • Luo J, Mitra S, Ludka T, Rezkalla SH, Sharma PP. Swallow Syncope: A Case Report and Review of the Literature. Clin Med Res. 2011 Nov;9(3-4):125-9.
    PubMed ID: 21263060
  • Kanth R, Berg RL, Rezkalla SH. Impact of lunar phase on the incidence of cardiac events. World Journal of Cardiovascular Diseases. 2012 Jul;2(3):124-128.
  • Schwartz GG, Olsson AG, Abt M, Ballantyne CM, Barter PJ, Brumm J, Chaitman B, Holme IM, Kallend D, Leiter LA, Leitersdorf E, McMurray JJV, Mundl H, Nicholls S, Shah PK, Tardif JC, Wright R, dal-OUTCOMES Investigators, Rezkalla SH. Effects of dalcetrapib in patients with a recent acute coronary syndrome. NEW ENGLAND JOURNAL OF MEDICINE. 2012 Nov;367(22):2089-99.
    PubMed ID: 23126252
  • Morrow D, Braunwald E, Bonaca M, Ameriso S, Dalby A, Fish M, Fox KA, Lipka L, Liu X, Nicolau J, Ophuis A, Paolasso E, Scirica B, Spinar J, Theroux P, Wiviott S, Strony J, Murphy S, TRA 2P-TIMI 50 Steering Committee and Investigators, Rezkalla SH. Vorapaxar in the secondary prevention of atherothrombotic events. NEW ENGLAND JOURNAL OF MEDICINE. 2012 Apr;366(15):1404-13.
    PubMed ID: 22443427
  • Kanth R, Ittaman S, Rezkalla SH. Circadian Patterns of ST Elevation Myocardial Infarction in the New Millennium. Clinical Medicine & Research. 2013 Jun;11(2):66-72.
    PubMed ID: 23580786
  • Sabbagh S, Henry Salzman MM, Kloner RA., Simkhovich B, Rezkalla SH. Remote Ischemic Preconditioning for Coronary Artery Bypass Graft Operations ANNALS OF THORACIC SURGERY. 2013 Aug;96(2):727-36.
    PubMed ID: 23816418
  • Mali P, Henry Salzman MM, Vidaillet HJ, Rezkalla SH. Amiodarone Therapy for Cardiac Arrhythmias: Is It Associated with the Development of Cancers? World Journal of Cardiovascular Diseases. 2014 Mar;4(3):109-118.
  • Rezkalla SH, Kloner R. Recreational marijuana use: is it safe for your patient? J Am Heart Assoc. 2014 Apr;3(2):e000904.
    PubMed ID: 24760963
  • VanWormer JJ, Miller AW, Rezkalla SH. Aspirin overutilization for the primary prevention of cardiovascular disease. Clin Epidemiol.. 2014 Dec;6 :433-40.
    PubMed ID: 25506245
  • VanWormer JJ, Miller AW, Rezkalla SH. Identifying opportunities to improve aspirin utilization for the primary prevention of cardiovascular disease in a regional health care system. WMJ. 2014 Nov;113(5):190-5; quiz 196.
    PubMed ID: 25739162
  • VanWormer JJ, Miller AW, Rezkalla SH. PS2-12: Opportunities to Improve Aspirin Utilization for the Primary Prevention of Cardiovascular Disease in a Regional Healthcare System Clinical Medicine & Research. 2014 Sep;12(1-2):Ps2-12.
  • Ittaman S, VanWormer JJ, Rezkalla SH. The Role of Aspirin in the Prevention of Cardiovascular Disease. Clinical Medicine & Research. 2014 Dec;12(3-4):147-54.
    PubMed ID: 24573704
  • Thomas G, Kloner R, Rezkalla SH. Adverse cardiovascular, cerebrovascular, and peripheral vascular effects of marijuana inhalation: what cardiologists need to know. AMERICAN JOURNAL OF CARDIOLOGY. 2014 Jan;113(1):187-90.
    PubMed ID: 24176069