• Burney Kieke MS

  • Biostatistician - Senior

    • MCRI - MCRI-Clin Epidem and Pop Hlth
    • 1000 North Oak Ave. ML2 Marshfield, WI 54449


Biostatistics, Emory University, Atlanta
MS, Statistics & Operations Research, New York University, New York
BS, Business Administration, University of Rhode Island, Kingston

Work Experience

2001 to Present:
Senior Epidemiologic Biostatistician, Center for Clinical Epidemiology and Population Health, Marshfield Clinic Research Institute, Marshfield
1996 to 2001:
Mathematical Statistician, Centers for Disease Control & Prevention, Atlanta
1994 to 1996:
Biostatistician, Klemm Analysis Group, Inc., Atlanta
1992 to 1994:
Senior Staff Consultant (Biostatistician), Orkand Corporation, Atlanta
1986 to 1988:
Reimbursement Analyst, Blue Cross & Blue Shield of Rhode Island, Providence
1984 to 1986:
Computer Programmer, Wakefield Data, Inc, Wakefield


Mr. Kieke is a biostatistician with more than twenty-five years of experience working on epidemiologic studies. He joined MCRI in 2001 after serving at the Centers for Disease Control and Prevention and the Agency for Toxic Substances and Disease Registry (CDC/ATSDR) for nine years. Mr. Kieke has formulated and implemented analysis plans addressing a broad range of research questions in areas such as vaccine safety/effectiveness, infectious disease incidence, antibiotic resistance, population-based health surveillance, reproductive health, waterborne disease and agriculture. These endeavors have utilized both standard study designs and more novel designs such as community intervention trials and rolling cross-sectional surveys. Before pursuing graduate studies in Statistics Mr. Kieke was employed as a computer programmer for four years. He has used the SAS software extensively throughout his career.

Mr. Kieke received a BS in Business Administration (Management Science, Management Information Systems) from the University of Rhode Island, an MS in Statistics and Operations Research from New York University and completed the required coursework for a PhD in Biostatistics at Emory University.

Research Interests

Epidemiologic Methods
Analysis of Clustered Data
Disease Surveillance

Select Publications

  • Heffron J, Samsami M, Juedemann S, Lavin J, Tavakoli Nick S, Kieke BA, Mayer BK. Mitigation of viruses of concern and bacteriophage surrogates via common unit processes for water reuse: A meta-analysis. Water Res.. 2024 March 15;252:121242. doi: 10.1016/j.watres.2024.121242.
    PubMed ID: 38342066
  • Weichelt B, Burke R, Kieke B, Pilz M, Shimpi N. Provider Adoption of mHealth in Rural Patient Care (Preprint). [published online ahead of print 2023 December 13]. JMIR Human Factors. doi: 10.2196/55443.
  • Esser NM, Su H, Coblentz WK, Akins MS, Kieke BA, Martin NP,...Jokela WE. Efficacy of recycled sand or organic solids as bedding sources for lactating cows housed in freestalls. J. Dairy Sci.. 2019 July; 102(7):6682-6698.
    PubMed ID: 31128869
  • Donahue JG, Kieke BA, King JP, Mascola MA, Shimabukuro TT, DeStefano F,...Belongia EA [including Hanson KE, McClure DL, Olaiya O.] Inactivated influenza vaccine and spontaneous abortion in the Vaccine Safety Datalink in 2012-13, 2013-14, and 2014-15. VACCINE. 2019 October 16; 37(44):6673-6681.
    PubMed ID: 31540812
  • VanWormer JJ, Kieke BA, Hanrahan LP, Pomeroy JJ, Mundy A, Schoeller DA. Circannual growth in Wisconsin children and adolescents: Identifying optimal periods of obesity prevention. [published online ahead of print 2019 October 8]. Pediatr Obes. :e12572.
    PubMed ID: 31595686
  • Donahue JG, Kieke BA, Lewis EM, Weintraub ES, Hanson KE, McClure DL,...Belongia EA [including Vickers ER.] Near Real-Time Surveillance to Assess the Safety of the 9-Valent Human Papillomavirus Vaccine. PEDIATRICS. 2019 December; 144(6)
    PubMed ID: 31740498
  • Belongia EA, King JP, Kieke BA, Pluta J, Al-Hilli A, Meece JK, Shinde V. Clinical Features, Severity, and Incidence of RSV Illness During 12 Consecutive Seasons in a Community Cohort of Adults =60 Years Old. Open Forum Infect Dis.. 2018 December;5(12):ofy316. doi: 10.1093/ofid/ofy316. PMCID: PMC6306566.
    PubMed ID: 30619907
  • Donahue JG, Kieke BA, King JP, DeStefano F, Mascola MA, Irving SA,...Belongia EA. (2017 September 25). Association of spontaneous abortion with receipt of inactivated influenza vaccine containing H1N1pdm09 in 2010-11 and 2011-12. VACCINE. 35(40):5314-5322.
    PubMed ID: 28917295
  • Burch TR, Spencer SK, Stokdyk JP, Kieke BA, Larson RA, Firnstahl AD,...Borchardt MA. (2017 August 16). Quantitative Microbial Risk Assessment for Spray Irrigation of Dairy Manure Based on an Empirical Fate and Transport Model. Environ Health Perspect. 125(8):087009.
    PubMed ID: 28885976
  • Bendixsen C, Barnes K, Kieke B, Schenk D, Simich J, Keifer M. Sorting Through the Spheres of Influence: Using Modified Pile Sorting to Describe Who Influences Dairy Farmers' Decision-Making About Safety. J Agromedicine. 2017 December; 22(4):316-327.
    PubMed ID: 28715252
  • Simpson MD, Kieke BA, Sundaram ME, McClure DL, Meece JK, Sifakis F,...Belongia EA. Incidence of Medically Attended Respiratory Syncytial Virus and Influenza Illnesses in Children 6-59 Months Old During Four Seasons. Open Forum Infect Dis.. 2016 April 21; 3(2):ofw081.
    PubMed ID: 27419158
  • Kieke AL, Kieke BA, Kopitzke SL, McClure DL, Belongia EA, VanWormer JJ, Greenlee RT. (2015 December). Validation of Health Event Capture in the Marshfield Epidemiologic Study Area. Clinical Medicine & Research. 13(3-4):103-11.
    PubMed ID: 25487238
  • McLean HQ, Thompson MG, Sundaram ME, Kieke BA, Gaglani M, Murthy K,...Belongia EA [including Meece JK.] Influenza Vaccine Effectiveness in the United States During 2012-13: Variable Protection by Age and Virus Type. JOURNAL OF INFECTIOUS DISEASES. 2015 May 15; 211(10):1529-40.
    PubMed ID: 25406334
  • Jackson ML, Jackson LA, Kieke B, McClure D, Gaglani M, Murthy K,...Thompson MG. (2015 September 22). Incidence of medically attended influenza infection and cases averted by vaccination, 2011/2012 and 2012/2013 influenza seasons. VACCINE. 33(39):5181-5187.
    PubMed ID: 26271827
  • Donahue JG, Kieke BA, Szilagy PG, Blumkin AK, Hilgemann DJ, Flanders WD,...Belongia EA [including Shay DK, Meece JK.] (2014 October). Can the rolling cross-sectional survey design be used to estimate the effectiveness of influenza vaccines? VACCINE. 32(48):6440-4.
    PubMed ID: 25284810
  • McClure DL, Kieke BA, Sundaram ME, Simpson M, Meece JK, Sifakis F,...Belongia EA. Seasonal incidence of medically attended respiratory syncytial virus infection in a community cohort of adults =50 years old. PLoS One. 2014 July 15; 9(7):e102586.
    PubMed ID: 25025344
  • Borchardt MA, Kieke BA, Spencer SK. (2013 September). Ranking filter methods for concentrating pathogens in lake water. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 79(17):5418-5419.
    PubMed ID: 23926086
  • Bateman A, Kieke BA, Irving SA, Meece JK, Shay DK, Belongia EA. (2013 April). Effectiveness of monovalent 2009 pandemic influenza A virus subtype H1N1 and 2010-2011 trivalent inactivated influenza vaccines in Wisconsin during the 2010-2011 influenza season. JOURNAL OF INFECTIOUS DISEASES. 207(8):1262-9.
    PubMed ID: 23341536
  • Irving SA, Kieke BA, Donahue JG, Mascola MA, Baggs J, DeStefano F,...for the Vaccine Safety Datalink [including Belongia EA.] (2013 January). Trivalent Inactivated Influenza Vaccine and Spontaneous Abortion. OBSTETRICS AND GYNECOLOGY. 121(1):159-165.
    PubMed ID: 23262941
  • Dharan N, Fry A, Kieke BA, Coleman LA, Meece JK, Vandermause MF,...Belongia EA. (2012 May). Clinical and virologic outcomes in patients with oseltamivir-resistant seasonal influenza A (H1N1) infections: results from a clinical trial. Influenza Other Respi Viruses. 6(3):153-8.
    PubMed ID: 22118629
  • Irving SA, Patel DC, Kieke BA, Donahue JG, Vandermause MF, Shay DK, Belongia EA. (2012 January). Comparison of clinical features and outcomes of medically attended influenza A and influenza B in a defined population over four seasons: 2004-2005 through 2007-2008. Influenza Other Respi Viruses. 6(1):37-43.
    PubMed ID: 21668663
  • Borchardt MA, Spencer SK, Kieke BA, Lambertini E, Loge F. (2012 September). Viruses in nondisinfected drinking water from municipal wells and community incidence of acute gastrointestinal illness. ENVIRONMENTAL HEALTH PERSPECTIVES. 120(9):1272-9.
    PubMed ID: 22659405
  • Lambertini E, Borchardt MA, Kieke BA, Spencer SK, Loge F. (2012 September). Risk of viral acute gastrointestinal illness from nondisinfected drinking water distribution systems. ENVIRONMENTAL SCIENCE & TECHNOLOGY. 46(17):9299-307.
    PubMed ID: 22839570
  • Coleman LA, Kieke BA, Irving SA, Shay DK, Vandermause MF, Lindstrom S, Belongia EA. (2011 January). Comparison of influenza vaccine effectiveness using different methods of case detection: Clinician-ordered rapid antigen tests vs. active surveillance and testing with real-time reverse-transcriptase polymerase chain reaction (rRT-PCR). VACCINE. 29(3):387-90.
    PubMed ID: 21095253
  • Belongia EA, Kieke BA, Donahue JG, Coleman LA, Irving SA, Meece JK,...Shay DK [including Vandermause MF.] (2011 July). Influenza vaccine effectiveness in Wisconsin during the 2007-08 season: Comparison of interim and final results. VACCINE. 29(38):6558-63.
    PubMed ID: 21767593
  • Lambertini E, Spencer SK, Kieke BA, Loge F, Borchardt MA. (2011 December). Virus contamination from operation and maintenance events in small drinking water distribution systems. JOURNAL OF WATER AND HEALTH. 9(4):799-812.
    PubMed ID: 22048438
  • Donahue JG, Kieke BA, Gargiullo PM, Jumaan AO, Berger NR, Mccauley JS, Belongia EA. (2010 June). Herpes Zoster and Exposure to the Varicella Zoster Virus in an Era of Varicella Vaccination. AMERICAN JOURNAL OF PUBLIC HEALTH. 100(6):1116-22.
    PubMed ID: 20075320
  • Belongia EA, Kieke BA, Donahue JG, Greenlee RT, Balish A, Foust A,...Marshfield Influenza Study Group. (2009 January). Effectiveness of inactivated influenza vaccines varied substantially with antigenic match from the 2004-2005 season to the 2006-2007 season. J Infect Dis. 199(2):159-67.
    PubMed ID: 19086915
  • Donahue JG, Kieke BA, Yih WK, Berger NR, Mccauley JS, Baggs J,...Vaccine Safety Datalink Team [including Belongia EA.] (2009 February). Varicella vaccination and ischemic stroke in children: is there an association? PEDIATRICS. 123(2):e228-34.
    PubMed ID: 19171574
  • Naleway AL, Belongia EA, Donahue JG, Kieke BA, Glanz JM, Vaccine Safety Datalink Team. (2009 December). Risk of immune hemolytic anemia in children following immunization. VACCINE. 27(52):7394-7.
    PubMed ID: 19766577
  • Belongia EA, Kieke BA, Coleman LA, Donahue JG, Irving SA, Meece JK,...Centers for Disease Control and Prevention (CDC) [including Vandermause MF.] (2008 April). Interim within-season estimate of the effectiveness of trivalent inactivated influenza vaccine--Marshfield, Wisconsin, 2007-08 influenza season. MMWR Morb Mortal Wkly Rep. 57(15):393-8.
    PubMed ID: 18418344
  • Lambertini E, Spencer SK, Bertz PD, Loge F, Kieke BA, Borchardt MA. (2008 May). Concentration of enteroviruses, adenoviruses, and noroviruses from drinking water by use of glass wool filters. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 74(10):2990-6.
    PubMed ID: 18359827
  • Rahman M, Vandermause MF, Kieke BA, Belongia EA. (2008 October). Performance of Binax NOW Flu A and B and direct fluorescent assay in comparison with a composite of viral culture or reverse transcription polymerase chain reaction for detection of influenza infection during the 2006 to 2007 season. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE. 62(2):162-6.
  • Rahman M, Bright RA, Kieke BA, Greenlee RT, Vandermause MF, Balish A,...Donahue JG [including Belongia EA.] (2008 January). Adamantane-resistant influenza infection during the 2004-05 season. EMERGING INFECTIOUS DISEASES. 14(1):173-176.
    PubMed ID: 18258102
  • Sannes MR, Belongia EA, Kieke BA, Smith K, Kieke AL, Vandermause MF,...Johnson JR. (2008 February). Predictors of antimicrobial-resistant Escherichia coli in the feces of vegetarians and newly hospitalized adults in Minnesota and Wisconsin. JOURNAL OF INFECTIOUS DISEASES. 197(3):430-4.
    PubMed ID: 18184093
  • Rahman M, Kieke BA, Vandermause MF, Mitchell PD, Greenlee RT, Belongia EA. (2007 August). Performance of Directigen flu A+B enzyme immunoassay and direct fluorescent assay for detection of influenza infection during the 2004-2005 season. Diagn Microbiol Infect Dis. 58(4):413-418.
    PubMed ID: 17509800
  • Gahr P, Harper J, Kieke BA, Como-Sabetti K, Craig Christianson R, Williams D,...Lynfield R. (2007 March). Healthcare professional surveys: judicious antibiotic use in Minnesota long-term care facilities. J Am Geriatr Soc. 55(3):473-474.
    PubMed ID: 17341259
  • Kieke AL, Borchardt MA, Kieke BA, Spencer SK, Vandermause MF, Smith KE,...Marshfield Enterococcal Study Group [including Belongia EA.] (2006 November). Use of streptogramin growth promoters in poultry and isolation of streptogramin-resistant enterococcus faecium from humans. J Infect Dis. 194(9):1200-1208.
    PubMed ID: 17041845
  • Greenlee RT, Zentner JL, Kieke BA, Elliott JL, Marlenga BL. (2005 May). Farm health surveillance in the Marshfield Epidemiologic Study Area: a pilot study. J Agric Saf Health. 11(2):211-218.
    PubMed ID: 15931947
  • Belongia EA, Kieke BA, Lynfield R, Davis JP, Besser R. (2005 January). Demand for prophylaxis after bioterrorism-related anthrax cases, 2001. Emerg Infect Dis. 11(1):42-48.
    PubMed ID: 15705321
  • Belongia EA, Naleway AL, Kieke BA, Qutaishat S, Casey C, Shay DK, Chen RT. (2005 February). Validation of a screening instrument to identify persons for exclusion from smallpox vaccination. Clin Infect Dis. 40(4):620-623.
    PubMed ID: 15712089
  • Kiang KM, Kieke BA, Como-Sabetti K, Lynfield R, Besser RE, Belongia EA. (2005 June). Clinician knowledge and beliefs after statewide program to promote appropriate antimicrobial drug use. Emerg Infect Dis. 11(6):904-911.
    PubMed ID: 15963286
  • Belongia EA, Knobloch MJ, Kieke BA, Davis JP, Janette C, Besser RE. (2005 June). Impact of statewide program to promote appropriate antimicrobial drug use. Emerg Infect Dis. 11(6):912-920.
    PubMed ID: 15963287
  • Hall MC, Kieke BA, Gonzales R, Belongia EA. (2004 July). Spectrum bias of a rapid antigen detection test for a group A beta-hemolytic streptococcal pharyngitis in a pediatric population. PEDIATRICS. 114(1):182-186.
    PubMed ID: 15231926
  • Yale SH, Mazza JJ, Kieke BA. (2004). Recurrent venothromboembolism in patients with and without anti-coagulation after inferior venal caval filter placement. JOURNAL OF GENERAL INTERNAL MEDICINE. 19(S1):204.
  • Greenlee RT, Marlenga BL, Zentner JL, Kieke BA, Elliott JL. (2003 September). Disease surveillance in the Marshfield Epidemiologic Study Area: focus on farm families. Ann Epidemiol. 13(8):568.
    PubMed ID: 12957004
  • Naleway AL, Belongia EA, Greenlee RT, Kieke BA, Chen RT, Shay DK. (2003 July). Eczematous skin disease and recall of past diagnoses: implications for smallpox vaccination. Ann Intern Med. 139(1):1-7.
    PubMed ID: 12834312
  • Heegeman DJ, Kieke BA. (2003 April). Learning curves, credentialing, and the need for ultrasound fellowships. Acad Emerg Med. 10(4):404-405.
    PubMed ID: 12670860
  • Heegeman DJ, Kieke B. (2003 April). Learning curves, credentialing, and the need for ultrasound fellowships. Acad Emerg Med. 10(4):404-5.
    PubMed ID: 12670860
  • Zane SB, Kieke BA, Kendrick JS, Bruce C. (2002 December). Surveillance in a time of changing health care practices: estimating ectopic pregnancy incidence in the United States. Matern Child Health J. 6(4):227-236.
    PubMed ID: 12512764
  • Fiscella K, Franks P, Kendrick JS, Meldrum S, Kieke BA. (2002 June). Risk of preterm birth that is associated with vaginal douching. Am J Obstet Gynecol. 186(6):1345-1350.
    PubMed ID: 12066120
  • Bruce FC, Kendrick JS, Kieke BA, Jagielski S, Joshi R, Tolsma DD. (2002 May). Is vaginal douching associated with preterm delivery? Epidemiology. 13(3):328-333.
    PubMed ID: 11964935
  • Keshavarz H, Hillis SD, Kieke BA, Marchbanks PA. (2002 July). Hysterectomy surveillance--United States, 1994-1999. MMWR CDC Surveill Summ. 51(No. SS-5):1-8.
  • MacKay AP, Kieke BA, Koonin LM, Beattie K. (2001 July). Tubal sterilization in the United States, 1994-1996. Fam Plann Perspect. 33(4):161-165.
    PubMed ID: 11496933
  • Duerr A, Kieke BA, Warren D, Shah K, Burk R, Peipert JF,...HER Study Group. (2001 March). Human papillomavirus-associated cervical cytologic abnormalities among women with or at risk of infection with human immunodeficiency virus. Am J Obstet Gynecol. 184(4):584-590.
    PubMed ID: 11262457
  • Warren D, Klein RS, Sobel J, Kieke BA, Brown W, Schuman P,...Duerr A. (2001). A multicenter study of bacterial vaginosis in women with or at risk for human immunodeficiency virus infection. Infect Dis Obstet Gynecol. 9(3):133-141.
    PubMed ID: 11516061
  • Blackmore-Prince C, Kieke BA, Kugaraj KA, Ferre C, Elam-Evans LD, Krulewitch CJ, Overpeck M. (1999 December). Racial differences in the patterns of singleton preterm delivery in the 1988 National Maternal and Infant Health Survey. Matern Child Health J. 3(4):189-197.
    PubMed ID: 10791359
  • Curtis KM, Hillis SD, Kieke BA, Brett KM, Marchbanks PA, Peterson HB. (1998 June). Visits to emergency departments for gynecologic disorders in the United States, 1992-1994. Obstet Gynecol. 91(6):1007-1012.
    PubMed ID: 9611014
  • Jones WK, Smith J, Kieke BA, Wilcox L. (1997 September). Female genital mutilation. Female circumcision. Who is at risk in the U.S.? Public Health Rep. 112(5):368-377.
    PubMed ID: 9323387
  • Lepine LA, Hillis SD, Marchbanks PA, Koonin LM, Morrow B, Kieke BA, Wilcox L. (1997 August). Hysterectomy surveillance--United States, 1980-1993. MMWR CDC Surveill Summ. 46(4):1-15.
    PubMed ID: 9259214
  • Thompson BL, Ponce de Leon R, Kieke BA, Velebil P, Wingo PA. (1997 February). Trends in hospitalizations for abnormal uterine bleeding in the United States: 1980-1992. J Womens Health. 6(1):73-81.
    PubMed ID: 9065376