• James Donahue DVM, PhD, MPH

  • Project Scientist II

    • MCRI - MCRI-Clin Epidem and Pop Hlth
    • 1000 North Oak Ave. ML2 Marshfield, WI 54449


BS, Biology, University of Minnesota, Saint Paul, MN
DVM, Zoonotic Diseases, University of Minnesota, Saint Paul, MN
MPH, Infectious Diseases, Harvard University School of Public Health, Boston, MA
1985 to 1988:
Epidemiology Fellow at FDA and NCI, National Institutes of Health, Washington
PhD, Epidemiology, Johns Hopkins School of Hygiene and Public Health, Baltimore, MD

Work Experience

1985 to 1987:
Epidemiology Fellow, USPHS Epidemiology Training Program, Epidemiology and Clinical Toxicology Unit, Center for Food Safety and Nutrition, Food and Drug Administration, Washington
1987 to 1988:
Guest Scientist, Environmental Epidemiology Branch, Division of Cancer Etiology, National Cancer Institute, Bethesda, MD
1988 to 1989:
Postdoctoral Position, Cancer Training Grant, National Cancer Institute and the Johns Hopkins School of Hygiene and Public Health, Baltimore, MD
1988 to 1992:
Project Director, Frequency of Agents Communicated by Transfusion Study and the Hepatitis C After Transfusion Study, The Johns Hopkins School of Hygiene and Public Health, Baltimore, MD
1992 to 2000:
Instructor in Medicine, Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
2000 to 2003:
Area Epidemiologist, Veterinary Services, Animal and Plant Health Inspection Service, United States Department of Agriculture, Madison, WI
2003 to Present:
Epidemiologist, Marshfield Clinic Research Institute, Marshfield, WI


Dr. Donahue is an epidemiologist with experience in infectious disease epidemiology and pharmacoepidemiology. He joined CCEPH in 2003 and is currently an investigator in the Vaccine Safety Datalink, a project in which Marshfield Clinic and several other medical care organizations received funding from CDC to investigate the safety of licensed vaccines using a large linked database. His current projects include studies of influenza vaccine safety during pregnancy and the safety of the 9-valent human papilloma virus vaccine.

Research Interests

Vaccine safety
Infectious disease epidemiology
Study design methodology

Select Publications

  • Donahue JG, Piesman J, Spielman A. (1987 January). Reservoir competence of white-footed mice for Lyme disease spirochetes. Am J Trop Med Hyg. 36(1):92-96.
    PubMed ID: 3812887
  • Donahue JG, Nelson KE, Munoz A, McAllister HA, Yawn DH, Cohen ND. (1990 December). Transmission of HIV by transfusion of screened blood. N Engl J Med. 323(24):1709.
    PubMed ID: 2233972
  • Donahue JG, Nelson KE, Munoz A, Vlahov D, Rennie LL, Taylor EL,...Farzadegan H. (1991 November). Antibody to hepatitis C virus among cardiac surgery patients, homosexual men, and intravenous drug users in Baltimore, Maryland. Am J Epidemiol. 134(10):1206-1211.
    PubMed ID: 1720924
  • Donahue JG, Munoz A, Ness PM, Brown DE, Yawn DH, McAllister HA,...Nelson KE. (1992 August). The declining risk of post-transfusion hepatitis C virus infection. N Engl J Med. 327(6):369-373.
    PubMed ID: 1320736
  • Donahue JG, Choo PW, Manson JE, Platt R. (1995 August). The incidence of herpes zoster. Arch Intern Med. 155(15):1605-1609.
    PubMed ID: 7618983
  • Donahue JG, Weiss ST, Livingston JM, Goetsch MA, Greineder DK, Platt R. (1997 March). Inhaled steroids and the risk of hospitalization for asthma. JAMA. 277(11):887-891.
    PubMed ID: 9062326
  • Choo PW, Donahue JG, Platt R. (1997 October). Ibuprofen and skin and soft tissue superinfections in children with varicella. Ann Epidemiol. 7(7):440-445.
    PubMed ID: 9349910
  • Donahue JG, Weiss ST, Goetsch MA, Livingston JM, Greineder DK, Platt R. (1997). Assessment of asthma using automated and full-text medical records. J Asthma. 34(4):273-281.
    PubMed ID: 9250251
  • Donahue JG, Andrade SE, Cain EM, DeFor TA, Goodman MF, Gurwitz JH, Platt R. (1998 November). Lamotrigine and severe skin eruptions. Pharmacoepidemiol Drug Saf. 7(6):415-417.
    PubMed ID: 15073972
  • Donahue JG, Greineder DK, Connor-Lacke L, Canning CF, Platt R. (1999 April). Utilization and cost of immunotherapy for allergic asthma and rhinitis. Ann Allergy Asthma Immunol. 82(4):339-347.
    PubMed ID: 10227332
  • Donahue JG, Fuhlbrigge AL, Finkelstein JA, Fagan J, Livingston JM, Lozano P,...Weiss KB. (2000 December). Asthma pharmacotherapy and utilization by children in 3 managed care organizations. The Pediatric Asthma Care Patient Outcomes Research Team. J Allergy Clin Immunol. 106(6):1108-1114.
    PubMed ID: 11112894
  • Chan KA, Andrade SE, Boles M, Buist DA, Chase GA, Donahue JG,...Platt R. (2000 June). Inhibitors of hydroxymethylglutaryl-coenzyme A reductase and risk of fracture among older women. Lancet. 355(9222):2185-2188.
    PubMed ID: 10881890
  • Kaye KS, Sands K, Donahue JG, Chan KA, Fishman P, Platt R. (2001 January). Preoperative drug dispensing as predictor of surgical site infection. Emerg Infect Dis. 7(1):57-65.
    PubMed ID: 11266295
  • Donahue JG, Chan KA, Andrade SE, Beck A, Boles M, Buist DS,...Platt R. (2002 April). Gastric and duodenal safety of daily alendronate. Arch Intern Med. 162(8):936-942.
    PubMed ID: 11966346
  • Andrade SE, Gurwitz JH, Chan KA, Donahue JG, Beck A, Boles M,...Platt R. (2002 March). Validation of diagnoses of peptic ulcers and bleeding from administrative databases: a multi-health maintenance organization study. J Clin Epidemiol. 55(3):310-313.
    PubMed ID: 11864803
  • Cohen ND, Donahue JG, Carey VJ, Seahorn JL, Piercy D, Donahoe JK,...Riddle TW. (2003 January). Case-control study of early-term abortions (early fetal losses) associated with mare reproductive loss syndrome in central Kentucky. J Am Vet Med Assoc. 222(2):210-217.
    PubMed ID: 12555985
  • Belongia EA, Coleman LA, Donahue JG. (2007 December). Effectiveness of Influenza Vaccination. N Engl J Med. 357(26):2728; author reply 2730-1.
    PubMed ID: 18160695
  • Mullooly JP, Donahue JG, DeStefano F, Baggs J, Eriksen E, VSD Data Quality Working Group. (2008). Predictive value of ICD-9-CM codes used in vaccine safety research. Methods Inf Med. 47(4):328-35.
    PubMed ID: 18690366
  • Belongia EA, Kieke BA, Donahue JG, Greenlee RT, Balish A, Foust A,...Marshfield Influenza Study Group. (2009 January). Effectiveness of inactivated influenza vaccines varied substantially with antigenic match from the 2004-2005 season to the 2006-2007 season. J Infect Dis. 199(2):159-67.
    PubMed ID: 19086915
  • Donahue JG, Kieke BA, Yih WK, Berger NR, Mccauley JS, Baggs J,...Vaccine Safety Datalink Team [including Belongia EA.] (2009 February). Varicella vaccination and ischemic stroke in children: is there an association? PEDIATRICS. 123(2):e228-34.
    PubMed ID: 19171574
  • Irving SA, Donahue JG, Shay DK, Ellis-Coyle TL, Belongia EA. (2009 November). Evaluation of self-reported and registry-based influenza vaccination status in a Wisconsin cohort. VACCINE. 27(47):6546-9.
    PubMed ID: 19729083
  • Naleway AL, Belongia EA, Donahue JG, Kieke BA, Glanz JM, Vaccine Safety Datalink Team. (2009 December). Risk of immune hemolytic anemia in children following immunization. VACCINE. 27(52):7394-7.
    PubMed ID: 19766577
  • Donahue JG, Kieke BA, Gargiullo PM, Jumaan AO, Berger NR, Mccauley JS, Belongia EA. (2010 June). Herpes Zoster and Exposure to the Varicella Zoster Virus in an Era of Varicella Vaccination. AMERICAN JOURNAL OF PUBLIC HEALTH. 100(6):1116-22.
    PubMed ID: 20075320
  • Donahue JG, Coleman LA, Bender J, Kempf DL, Vandermause MF, McGraw PJ,...Belongia EA. (2011 September). Prospective Study of Avian Influenza Infection in Backyard Poultry Flocks and Flock Handlers in Wisconsin. Vector Borne Zoonotic Dis. 11(9):1293-7.
    PubMed ID: 21612537
  • Belongia EA, Kieke BA, Donahue JG, Coleman LA, Irving SA, Meece JK,...Shay DK [including Vandermause MF.] (2011 July). Influenza vaccine effectiveness in Wisconsin during the 2007-08 season: Comparison of interim and final results. VACCINE. 29(38):6558-63.
    PubMed ID: 21767593
  • McCarthy NL, Gee J, Weintraub E, Donahue JG, Nordin JD, Daley MF,...Baggs J. (2011 July). Monitoring vaccine safety using the Vaccine Safety Datalink: Utilizing immunization registries for pandemic influenza. VACCINE. 29(31):4891-6.
    PubMed ID: 21596088
  • Irving SA, Patel DC, Kieke BA, Donahue JG, Vandermause MF, Shay DK, Belongia EA. (2012 January). Comparison of clinical features and outcomes of medically attended influenza A and influenza B in a defined population over four seasons: 2004-2005 through 2007-2008. Influenza Other Respi Viruses. 6(1):37-43.
    PubMed ID: 21668663
  • Glanz JM, Newcomer S, Narwaney K, Hambidge SJ, Daley MF, Wagner N,...Weintraub ES [including Donahue JG.] (2013 March). A population-based cohort study of undervaccination in 8 managed care organizations across the United States. JAMA Pediatr. 167(3):274-81.
    PubMed ID: 23338829
  • McCarthy NL, Weintraub E, Vellozzi C, Duffy J, Gee J, Donahue JG,...DeStefano F. (2013). Mortality Rates and Cause-of-Death Patterns in a Vaccinated Population AMERICAN JOURNAL OF PREVENTIVE MEDICINE. 45(1):91-97.
  • Tseng H, Sy L, Qian L, Marcy SM, Jackson LA, Glanz J,...Vaccine Safety Datalink Team [including Donahue JG.] (2013 February). Safety of a Tetanus-Diphtheria-Acellular Pertussis Vaccine When Used Off-Label in an Elderly Population. CLINICAL INFECTIOUS DISEASES. 56(3):315-321.
    PubMed ID: 23196953
  • Irving SA, Kieke BA, Donahue JG, Mascola MA, Baggs J, DeStefano F,...for the Vaccine Safety Datalink [including Belongia EA.] (2013 January). Trivalent Inactivated Influenza Vaccine and Spontaneous Abortion. OBSTETRICS AND GYNECOLOGY. 121(1):159-165.
    PubMed ID: 23262941
  • Jackson LA, Peterson D, Nelson JC, Marcy SM, Naleway AL, Nordin JD,...Weintraub E [including Donahue JG.] (2013 February). Vaccination Site and Risk of Local Reactions in Children 1 Through 6 Years of Age. PEDIATRICS. 131(2):283-9.
    PubMed ID: 23319538
  • Tseng H, Sy L, Liu I, Qian L, Marcy SM, Weintraub E,...Jacobsen SJ [including Donahue JG.] (2013 May). Postlicensure surveillance for pre-specified adverse events following the 13-valent pneumococcal conjugate vaccine in children. VACCINE. 31(22):2578-83.
    PubMed ID: 23579258
  • McCarthy NL, Irving SA, Donahue JG, Weintraub E, Gee J, Belongia EA, Baggs J. (2013 December). Vaccination coverage levels among children enrolled in the Vaccine Safety Datalink. VACCINE. 31(49):5822-6.
    PubMed ID: 24135576
  • Hechter R, Qian L, Sy L, Greene SK, Weintraub ES, Naleway AL,...Jacobsen SJ [including Donahue JG.] (2013 February). Secular trends in diagnostic code density in electronic healthcare data from health care systems in the Vaccine Safety Datalink Project. VACCINE. 31(7):1080-5.
    PubMed ID: 23267842
  • Donahue JG, Kieke BA, Szilagy PG, Blumkin AK, Hilgemann DJ, Flanders WD,...Belongia EA [including Shay DK, Meece JK.] (2014 October). Can the rolling cross-sectional survey design be used to estimate the effectiveness of influenza vaccines? VACCINE. 32(48):6440-4.
    PubMed ID: 25284810
  • Cheetham TC, Marcy SM, Tseng HF, Sy LS, Liu IL, Bixler F,...Jacobsen SJ [including Donahue JG.] (2015 July). Risk of Herpes Zoster and Disseminated Varicella Zoster in Patients Taking Immunosuppressant Drugs at the Time of Zoster Vaccination. Mayo Clin Proc. 90(7):865-73.
    PubMed ID: 26051268
  • Szilagyi PG, Blumkin A, Treanor JJ, Gallivan S, Albertin C, Lofthus GK,...Shay DK [including Donahue JG.] (2016 July). Incidence and viral aetiologies of acute respiratory illnesses (ARIs) in the United States: a population-based study. Epidemiol Infect.. 144(10):2077-2086.
    PubMed ID: 26931351
  • Naleway AL, Crane B, Smith N, Daley MF, Donahue J, Gee J,...Weintraub ES. (2016 January 2). Absence of venous thromboembolism risk following quadrivalent human papillomavirus vaccination, Vaccine Safety Datalink, 2008-2011. VACCINE. 34(1):167-71.
    PubMed ID: 26549361
  • Klein NP, Lewis E, McDonald J, Fireman B, Naleway A, Glanz J,...Baxter R [including Donahue JG.] (2017 March 14). Risk factors and familial clustering for fever 7-10days after the first dose of measles vaccines. VACCINE. 35(12):1615-1621.
    PubMed ID: 28233624
  • Donahue JG, Kieke BA, King JP, DeStefano F, Mascola MA, Irving SA,...Belongia EA. (2017 September 25). Association of spontaneous abortion with receipt of inactivated influenza vaccine containing H1N1pdm09 in 2010-11 and 2011-12. VACCINE. 35(40):5314-5322.
    PubMed ID: 28917295
  • Qian L, Sy LS, Hong V, Glenn SC, Ryan DS, Nelson JC,...Xu S [including Donahue JG.] Impact of the COVID-19 Pandemic on Health Care Utilization in the Vaccine Safety Datalink: Retrospective Cohort Study. JMIR Public Health Surveill. 2024 January 23;10:e48159. doi: 10.2196/48159. PMCID: PMC10807656.
    PubMed ID: 38091476
  • Zerbo O, Bartlett J, Fireman B, Lewis N, Goddard K, Dooling K,...Klein NP [including Donahue JG.] Effectiveness of Recombinant Zoster Vaccine Against Herpes Zoster in a Real-World Setting. [published online ahead of print 2024 January 9]. Ann Intern Med. doi: 10.7326/M23-2023.
    PubMed ID: 38190712
  • King JP, Chung JR, Donahue JG, Martin ET, Leis AM, Monto AS,...Belongia EA. Post-recovery health domain scores among outpatients by SARS-CoV-2 testing status during the pre-Delta period. BMC Infect Dis. 2024 March 8;24(1):300. doi: 10.1186/s12879-024-09108-3. PMCID: PMC10921777.
    PubMed ID: 38454352