• Huong Nguyen PhD, MPH

  • Research Scientist

    • MCRI - MCRI-Clin Epidem and Pop Hlth
    • 1000 North Oak Ave. ML2 Marshfield, WI 54449


PhD, Epidemiology, University of Washington, Seattle, WA
MPH, Epidemiology, University of Minnesota, Minneapolis, MN
BA, Chemistry, College of Saint Benedict, Saint Joseph, MN
Advance Vaccinology, Fondation Mérieux, Veyrier du Lac, France

Work Experience

2002 to 2004:
Research Fellow, National Immunization Program, Centers for Disease Control and Prevention, Associations of Schools of Public Health, Atlanta, GA
2004 to 2008:
Pre-doctoral Research Associate, Department of Epidemiology, Virology Research Clinic, University of Washington, Seattle, WA
2008 to 2012:
Epidemiologist, Division of Viral Diseases, National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, GA
2012 to Present:
Research Scientist, Marshfield Clinic Research Institute, Marshfield, WI


Dr. (McLean) Nguyen is an epidemiologist with focus on infectious diseases and vaccine effectiveness, immunogenicity, safety, promotion, and policy. The majority of her research is on influenza, addressing issues relating to prior vaccination history and vaccine effectiveness, both clinically and immunologically. More recently, her research has expanded to include assessment of SARS-CoV-2, RSV, and other respiratory viruses: transmission in households, incidence in a community cohort, and COVID-19 vaccine effectiveness. Her research also includes improving health of pregnant people and their infants, promoting adolescent vaccinations, lyme disease, and acute gastroenteritis.

From 2008-2012, Dr. Nguyen worked in the Division of Viral Diseases at CDC. She was involved in multiple studies and outbreak investigations for vaccine preventable diseases, served as a WHO consultant on polio eradication in Kenya, and served as the CDC secretariat for the Advisory Committee on Immunization Practices (ACIP) work group on measles, mumps, and rubella vaccine.

Research Interests

-Acute gastroenteritis
-Antimicrobial stewardship
-COVID-19 and SARS-CoV-2
-Household transmission
-Human papillomavirus (HPV)
-Infectious diseases
-Longitudinal cohorts
-Maternal/child health
-Measles, mumps, rubella (MMR)
-Respiratory Syncytial Virus (RSV)
-Vaccine effectiveness, immunogencity, safety, policy, and promotion

Select Publications

  • Belongia EA, Petrie JG, Feldstein LR, Guan L, Halfmann PJ, King JP,...Kawaoka Y [including McLean HQ.] Neutralizing Immunity Against Antigenically Advanced Omicron BA.5 in Children After SARS-CoV-2 Infection. J Pediatric Infect Dis Soc. 2024 January 29;13(1):100-104. doi: 10.1093/jpids/piad109.
    PubMed ID: 38142128
  • Alonge, OD, Marin, M, Hickman, CJ, Sowers, SB, Chen, M, Hao, L,...Nguyen, Huong. Long-term Neutralizing Antibody Levels Against Measles and Rubella Viruses among Adults with Three Doses of Measles-Mumps-Rubella Vaccine. [published online ahead of print 2024 January 3]. Open Forum Infectious Diseases. 11(1). doi: https://doi.org/10.1093/ofid/ofad700. PMCID: PMC10783245.
    PubMed ID: 38213634
  • Alonge OD, Marin M, Hickman CJ, Sowers SB, Chen MH, Hao L,...Nguyen HQ [including McClure DL.] Long-term Neutralizing Antibody Levels Against Measles and Rubella Viruses Among Adults With 3 Doses of Measles-Mumps-Rubella Vaccine. Open Forum Infect Dis.. 2024 January;11(1):ofad700. doi: 10.1093/ofid/ofad700. PMCID: PMC10783245.
    PubMed ID: 38213634
  • Pattinson D, Jester P, Gu C, Guan L, Armbrust T, Petrie JG,...Kawaoka Y [including King JP, Nguyen HQ, Belongia EA.] Ipsilateral and contralateral coadministration of influenza and COVID-19 vaccines produce similar antibody responses. EBioMedicine. 2024 May;103:105103. doi: 10.1016/j.ebiom.2024.105103.
    PubMed ID: 38574407
  • Petrie JG, Pattinson D, King JP, Neumann G, Guan L, Jester P,...Nguyen HQ [including Meece JK, Kieke BA, Belongia EA.] SARS-CoV-2 incidence, seroprevalence, and antibody dynamics in a rural, population-based cohort: March 2020 - July 2022. [published online ahead of print 2024 June 17]. Am J Epidemiol. kwae125. doi: 10.1093/aje/kwae125.
    PubMed ID: 38885957
  • Rolfes MA, Talbot HK, McLean HQ, Stockwell MS, Ellingson KD, Lutrick K,...Belongia, EA [including Meece JK.] Household Transmission of Influenza A Viruses in 2021-2022. JAMA. 2023 February 14; 329(6):482-489. doi: 10.1001/jama.2023.0064. PMCID: PMC9880862.
    PubMed ID: 36701144
  • McLean HQ, Petrie JG, Hanson KE, Meece JK, Rolfes MA, Sylvester GC,...Belongia EA. Interim Estimates of 2022-23 Seasonal Influenza Vaccine Effectiveness - Wisconsin, October 2022-February 2023. MMWR Morb Mortal Wkly Rep. 2023 February 24; 72(8):201-205. doi: 10.15585/mmwr.mm7208a1. PMCID: PMC9949852.
    PubMed ID: 36821715
  • Hanson KE, Marin M, Daley MF, Groom HC, Jackson LA, Sy LS,...McLean HQ [including Belongia EA.] Safety of measles, mumps, and rubella vaccine in adolescents and adults in the vaccine safety Datalink. Vaccine X. 2023 February 4; 13 :100268. PMCID: PMC9939709.
    PubMed ID: 36814595
  • Petrie JG, King JP, McClure DL, Rolfes MA, Meece JK, Pattinson D,...McLean HQ [including Belongia EA.] Effectiveness of first and second COVID-19 mRNA vaccine monovalent booster doses during a period of circulation of Omicron variant sublineages: December 2021-July 2022. Influenza Other Respir Viruses.. 2023 March; 17(3):e13104. doi: 10.1111/irv.13104. PMCID: PMC9975792.
    PubMed ID: 36875208
  • Alonge, O, Hanson K, Eggebrecht M, Funk P, Christianson B, Williams C,...McLean H [including Belongia E.] COVID-19 Booster Dose Reminder/Recall for Adolescents: Findings From a Health-Care System in Wisconsin. Journal of Adolescent Health. 2023 November 21; 73(5):953-956. doi: 10.1016/j.jadohealth.2023.06.026.
    PubMed ID: 37610391
  • Polter EJ, Christianson B, Steinberg A, Doan M, Ljungman H, Sundaram ME,...Bendixsen C [including VanWormer JJ, McLean HQ.] Urban and rural healthcare providers' perspectives on HPV vaccination in Minnesota. Hum Vaccin Immunother. 2023 December 15;19(3):2291859. doi: 10.1080/21645515.2023.2291859. PMCID: PMC10730133.
    PubMed ID: 38095606
  • McLean HQ, McClure DL, King JP, Meece JK, Pattinson D, Neumann G,...Belongia EA. mRNA COVID-19 vaccine effectiveness against SARS-CoV-2 infection in a prospective community cohort, rural Wisconsin, November 2020 to December 2021. Influenza Other Respir Viruses.. 2022 July; 16(4):607-612.
    PubMed ID: 35178857
  • McLean HQ, Grijalva CG, Hanson KE, Zhu Y, Deyoe JE, Meece JK,...Rolfes MA [including Belongia EA.] Household Transmission and Clinical Features of SARS-CoV-2 Infections. [published online ahead of print 2022 February 23]. PEDIATRICS.
    PubMed ID: 35194642
  • Boyce TG, Christianson B, Hanson KE, Dunn D, Polter E, VanWormer JJ,...McLean HQ [including Belongia EA.] Factors associated with human papillomavirus and meningococcal vaccination among adolescents living in rural and urban areas. Vaccine X. 2022 August 11; 11 :100180. PMCID: PMC9218554.
    PubMed ID: 35755142
  • Goessl CL, Christianson B, Hanson KE, Polter EJ, Olson SC, Boyce TG,...VanWormer JJ [including Belongia EA, McLean HQ.] Human papillomavirus vaccine beliefs and practice characteristics in rural and urban adolescent care providers. BMC Public Health.. 2022 July 9; 22(1):1322.
    PubMed ID: 35810274
  • Marin M, Fiebelkorn AP, Bi D, Coleman LA, Routh J, Curns AT, McLean HQ. Adverse Events among Young Adults following a Third Dose of Measles-Mumps-Rubella Vaccine. Clin Infect Dis. 2021 October 5; 73(7):e1546-e1553.
    PubMed ID: 32766827
  • Rolfes MA, Grijalva CG, Zhu Y, McLean HQ, Hanson KE, Belongia EA,...Fry AM [including Meece J.] Implications of Shortened Quarantine Among Household Contacts of Index Patients with Confirmed SARS-CoV-2 Infection - Tennessee and Wisconsin, April-September 2020. MMWR Morb Mortal Wkly Rep. 2021 January 1; 69(5152):1633-1637.
    PubMed ID: 33382676
  • King JP, McLean HQ, Belongia EA. Risk of symptomatic severe acute respiratory syndrome coronavirus 2 infection not associated with influenza vaccination in the 2019-2020 season. Influenza Other Respir Viruses.. 2021 November; 15(6):697-700.
    PubMed ID: 34169670
  • Kim SS, Chung JR, Belongia EA, McLean HQ, King JP, Nowalk MP,...Flannery B. mRNA Vaccine Effectiveness against COVID-19 among Symptomatic Outpatients Aged =16 Years in the United States, February - May 2021. J Infect Dis. 2021 November 22; 224(10):1694-1698.
    PubMed ID: 34498052
  • McLean HQ, Levine MZ, King JP, Flannery B, Belongia EA. Serologic response to sequential vaccination with enhanced influenza vaccines: Open label randomized trial among adults aged 65-74 years. VACCINE. 2021 December 3; 39(49):7146-7152.
    PubMed ID: 34774360
  • McLean HQ, King JP, Talley P, Flannery B, Spencer S, Levine MZ,...Belongia EA. Effect of Previous-Season Influenza Vaccination on Serologic Response in Children During 3 Seasons, 2013-2014 Through 2015-2016. J Pediatric Infect Dis Soc. 2020 April 30; 9(2):173-180.
    PubMed ID: 30759228
  • McLean HQ, Hanson KE, Foster AD, Olson SC, Kemble SK, Belongia EA. Serious outcomes of medically attended, laboratory-confirmed influenza illness among school-aged children with and without asthma, 2007-2018. Influenza Other Respir Viruses.. 2020 March; 14(2):173-181.
    PubMed ID: 31944583
  • McLean HQ, Belongia EA. Influenza Vaccine Effectiveness: New Insights and Challenges. [published online ahead of print 2020 January 27]. Cold Spring Harb Perspect Med.
    PubMed ID: 31988202
  • Scallan Walter EJ, McLean HQ, Griffin PM. Hospital Discharge Data Underascertain Enteric Bacterial Infections Among Children. [published online ahead of print 2020 February 24]. Foodborne Pathog Dis.
    PubMed ID: 32091947
  • Belongia EA, Levine MZ, Olaiya O, Gross FL, King JP, McLean HQ, Flannery B. Clinical trial to assess immunogenicity of high-dose, adjuvanted, and recombinant influenza vaccines against cell-grown A(H3N2) viruses in adults 65 to 74 years, 2017-2018. [published online ahead of print 2020 March 4]. VACCINE.
    PubMed ID: 32145994
  • Arevalo P, McLean HQ, Belongia EA, Cobey S. Earliest infections predict the age distribution of seasonal influenza A cases. [published online ahead of print 2020 July 7]. Elife. 9
    PubMed ID: 32633233
  • Grijalva CG, Rolfes MA, McLean HQ, Hanson KE, Belongia EA, Halasa NB,...Talbot HK. Transmission of SARS-COV-2 Infections in Households - Tennessee and Wisconsin, April-September 2020. MMWR Morb Mortal Wkly Rep. 2020 November 6; 69(44):1631-1634. doi: 10.15585/mmwr.mm6944e1.
    PubMed ID: 33151916
  • Belongia EA, McLean HQ. Influenza Vaccine Effectiveness: Defining the H3N2 Problem. Clin Infect Dis. 2019 October 30; 69(10):1817-1823.
    PubMed ID: 31102401
  • Hanson KE, McLean HQ, Belongia EA, Stokley S, McNeil MM, Gee J, VanWormer JJ. Sociodemographic and clinical correlates of human papillomavirus vaccine attitudes and receipt among Wisconsin adolescents. Papillomavirus Res. 2019 December; 8 :100168. PMCID: PMC6556618.
    PubMed ID: 31136831
  • McLean HQ, Orenstein WA. Protecting Young Infants From Measles. PEDIATRICS. 2019 December 1; 144(6)
    PubMed ID: 31753912
  • Seagle EE, Bednarczyk RA, Hill T, Fiebelkorn AP, Hickman CJ, Icenogle JP,...McLean HQ [including Belongia EA.] Measles, mumps, and rubella antibody patterns of persistence and rate of decline following the second dose of the MMR vaccine. VACCINE. 2018 February 1; 36(6):818-826.
    PubMed ID: 29317117
  • King JP, McLean HQ, Meece JK, Levine MZ, Spencer SM, Flannery B, Belongia EA. Vaccine failure and serologic response to live attenuated and inactivated influenza vaccines in children during the 2013-2014 season. VACCINE. 2018 February 21; 36(9):1214-1219.
    PubMed ID: 29395525
  • King JP, McLean HQ, Belongia EA. Validation of Self-Reported Influenza Vaccination in the Current and Prior Season. Influenza Other Respir Viruses.. 2018 November; 12(6):808-813.
    PubMed ID: 30028081
  • McLean HQ, Fiebelkorn AP, Ogee-Nwankwo A, Hao L, Coleman LA, Adebayo A, Icenogle JP. Rubella virus neutralizing antibody response after a third dose of measles-mumps-rubella vaccine in young adults. VACCINE. 2018 September 11; 36(38):5732-5737.
    PubMed ID: 30107992
  • Frost HM, McLean HQ, Chow BDW. Variability in Antibiotic Prescribing for Upper Respiratory Illnesses by Provider Specialty. J Pediatr. 2018 December; 203 :76-85.
    PubMed ID: 30195553
  • McLean HQ, Caspard H, Griffin MR, Gaglani M, Peters TR, Poehling KA,...Belongia EA. Association of Prior Vaccination With Influenza Vaccine Effectiveness in Children Receiving Live Attenuated or Inactivated Vaccine. JAMA Netw Open. 2018 October 5; 1(6):e183742.
    PubMed ID: 30646262
  • Scallan E, Griffin PM, McLean HQ, Mahon BE. Hospitalisations due to bacterial gastroenteritis: A comparison of surveillance and hospital discharge data. Epidemiol Infect.. 2018 June; 146(8):954-960.
    PubMed ID: 29655383
  • Barnes KL, VanWormer JJ, Stokley S, Vickers ER, McLean HQ, Belongia EA, Bendixsen CG. Determinants of human papillomavirus vaccine attitudes: an interview of Wisconsin parents. BMC Public Health.. 2018 June 15; 18(1):746.
    PubMed ID: 29907115
  • McLean HQ, Peterson SH, King JP, Meece JK, Belongia EA. (2017 May). School absenteeism among school-aged children with medically attended acute viral respiratory illness during three influenza seasons, 2012-2013 through 2014-2015. Influenza Other Respi Viruses. 11(3):220-229.
    PubMed ID: 27885805
  • Belongia EA, Skowronski DM, McLean HQ, Chambers C, Sundaram ME, De Serres G. Repeated annual influenza vaccination and vaccine effectiveness: review of evidence. Expert Rev Vaccines. 2017 July; 16(7):1-14.
    PubMed ID: 28562111
  • McLean HQ, VanWormer JJ, Chow BDW, Birchmeier B, Vickers E, DeVries E,...Belongia EA. (2017 August). Improving Human Papillomavirus Vaccine Use in an Integrated Health System: Impact of a Provider and Staff Intervention. J Adolesc Health. 61(2):252-258.
    PubMed ID: 28462786
  • McLean HQ, Caspard H, Griffin MR, Poehling KA, Gaglani M, Belongia EA,...Ambrose CS. (2017 May 9). Effectiveness of live attenuated influenza vaccine and inactivated influenza vaccine in children during the 2014-2015 season. VACCINE. 35(20):2685-2693.
    PubMed ID: 28408121
  • Van Wormer JJ, King JP, Gajewski A, McLean HQ, Belongia EA. (2017 Dec). Influenza and Workplace Productivity Loss in Working Adults. J Occup Environ Med. 59(12):1135-1139.
    PubMed ID: 28759481
  • VanWormer JJ, Bendixsen CG, Vickers ER, Stokley S, McNeil MM, Gee J,...McLean HQ [including Belongia EA.] Association between parent attitudes and receipt of human papillomavirus vaccine in adolescents. BMC Public Health.. 2017 October 2; 17(1):766.
    PubMed ID: 28969653
  • Belongia EA, Simpson MD, King JP, Sundaram ME, Kelley NS, Osterholm MT, McLean HQ. Variable influenza vaccine effectiveness by subtype: a systematic review and meta-analysis of test-negative design studies. Lancet Infect Dis. 2016 August; 16(8):942-951.
    PubMed ID: 27061888
  • McLean HQ, Chow BD, VanWormer JJ, King JP, Belongia EA. (2016 October 15). Effect of Statin Use on Influenza Vaccine Effectiveness. J Infect Dis. 214(8):1150-1158.
    PubMed ID: 27471318
  • McLean HQ, Thompson MG, Sundaram ME, Kieke BA, Gaglani M, Murthy K,...Belongia EA [including Meece JK.] Influenza Vaccine Effectiveness in the United States During 2012-13: Variable Protection by Age and Virus Type. JOURNAL OF INFECTIOUS DISEASES. 2015 May 15; 211(10):1529-40.
    PubMed ID: 25406334
  • McLean HQ, Belongia EA, Kieke BA, Meece JK, Fry AM. Impact of Late Oseltamivir Treatment on Influenza Symptoms in the Outpatient Setting: Results of a Randomized Trial. Open Forum Infect Dis. 2015 September; 2(3):ofv100. PMCID: PMC4525010.
    PubMed ID: 26258157
  • McLean HQ, Thompson MG, Sundaram ME, Meece JK, McClure DL, Friedrich T, Belongia EA. Impact of Repeated Vaccination on Vaccine Effectiveness Against Influenza A(H3N2) and B During 8 Seasons. Clin Infect Dis.. 2014 November 15; 59(10):1375-85.
    PubMed ID: 25270645
  • Kutty P, McLean HQ, Lawler J, Schulte C, Hudson J, Blog D, Wallace G. (2014 February). Risk Factors for Transmission of Mumps in a Highly Vaccinated Population in Orange County, New York, 2009-2010. PEDIATRIC INFECTIOUS DISEASE JOURNAL. 33(2):121-5.
    PubMed ID: 23995590
  • McLean HQ, Meece JK, Belongia EA. (2014 January). Influenza vaccination and risk of hospitalization among adults with laboratory confirmed influenza illness. VACCINE. 32(4):453-7.
    PubMed ID: 24291201
  • McLean HQ, Fiebelkorn AParker, Temte JL, wallace GS. (2013 June). Prevention of Measles, Rubella, Congenital Rubella Syndrome, and Mumps, 2013: Summary Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep.. 62(RR-04):1-34.
    PubMed ID: 23760231
  • Marin M, Nguyen HQ, Langidrik J, Edwards R, Briand K, Papania M,...LeBaron CW. (2006 February). Measles transmission and vaccine effectiveness during a large outbreak on a densely populated island: implications for vaccination policy. CLINICAL INFECTIOUS DISEASES. 42(3):315-9.
    PubMed ID: 16392073
  • Nguyen HQ, Jumaan AO, Seward J. (2005 February). Decline in mortality due to varicella after implementation of varicella vaccination in the United States. NEW ENGLAND JOURNAL OF MEDICINE. 352(5):450-8.
    PubMed ID: 15689583
  • Marin M, Nguyen HQ, Keen J, Jumaan AO, Mellen P, Hayes E,...Seward J. (2005 April). Importance of catch-up vaccination: experience from a varicella outbreak, Maine, 2002-2003. PEDIATRICS. 115(4):900-5.
    PubMed ID: 15805362