Clinical Trials
Enrolling Trials
31-40 of 151
A031702, A Phase II Study of Ipilimumab, Cabozantinib, and Nivolumab in Rare Genitourinary Cancers (ICONIC)
Husak, Michael
Bladder, Prostate, Kidney - Rare
Adult
This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that have spread to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving cabozantinib, nivolumab, and ipilimumab may work better in treating patients with genitourinary tumors that have no treatment options compared to giving cabozantinib, nivolumab, or ipilimumab alone.
Wilson, Anna E
(715) 858-6860
Diagnostic & Treatment Center
3401 CRANBERRY BLVD
WESTON, WI 54476
Eau Claire Center
2116 Craig Rd
Eau Claire, WI 54701
Marshfield Medical Center - Rice Lake
1700 W STOUT ST
RICE LAKE, WI 54868
Minocqua Center
9601 TOWNLINE RD
MINOCQUA, WI 54548
MMC - Marshfield
1000 N OAK AVE
MARSHFIELD, WI 54449
Stevens Point Center
,
Wausau Center
2727 PLAZA DRIVE
WAUSAU, WI 54401
Weston Center
3501 CRANBERRY BLVD
WESTON, WI 54476
A031803, Phase II Trial of Intravesical Gemcitabine and MK-3475 (Pembrolizumab) in the Treatment of Patients With BCG-Unresponsive Non-Muscle Invasive Bladder Cancer
Husak, Michael
Bladder, Prostate, Kidney - Bladder/Ureter
Adult
This phase II trial studies how well gemcitabine together with pembrolizumab works in treating patients with non-muscle invasive bladder cancer who are unresponsive to the BCG vaccine. Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Adding pembrolizumab to gemcitabine may delay the return of bladder cancer for longer than gemcitabine alone.
Wilson, Anna E
(715) 858-6860
Diagnostic & Treatment Center
3401 CRANBERRY BLVD
WESTON, WI 54476
Eau Claire Center
2116 Craig Rd
Eau Claire, WI 54701
Marshfield Clinic Cancer Center - Eau Claire
2200 Craig Road
Eau Claire, WI 54701
Marshfield Medical Center - Rice Lake
1700 W STOUT ST
RICE LAKE, WI 54868
Minocqua Center
9601 TOWNLINE RD
MINOCQUA, WI 54548
MMC - Marshfield
1000 N OAK AVE
MARSHFIELD, WI 54449
Stevens Point Center
,
Wausau Center
2727 PLAZA DRIVE
WAUSAU, WI 54401
Weston Center
3501 CRANBERRY BLVD
WESTON, WI 54476
A032101-A Phase 2 Trial of ADT Interruption in Patients
Responding Exceptionally to AR-Pathway Inhibitor in
Metastatic Hormone-Sensitive Prostate Cancer (MHSPC):
A-DREAM
Fagbemi, Seth O
Bladder, Prostate, Kidney - Prostate
Adult
This phase II trial examines antiandrogen therapy interruptions in patients with hormone-sensitive prostate cancer that has spread to other places in the body (metastatic) responding exceptionally well to androgen receptor-pathway inhibitor therapy. The usual treatment for patients with metastatic prostate cancer is to receive hormonal medications including a medication to decrease testosterone levels in the body and a potent oral hormonal medication to block growth signals from male hormones (like testosterone) in the cancer cells. Patients whose cancer is responding exceptionally well to this therapy may take a break from these medications according to their doctor's guidance. This trial may help doctors determine if stopping treatment can allow for testosterone recovery.
Revels, Cheryl M
(715) 389-4177
Marshfield Clinic Cancer Center - Eau Claire
2200 Craig Road
Eau Claire, WI 54701
Marshfield Medical Center - Rice Lake
1700 W STOUT ST
RICE LAKE, WI 54868
Minocqua Center
9601 TOWNLINE RD
MINOCQUA, WI 54548
MMC - Marshfield
1000 N OAK AVE
MARSHFIELD, WI 54449
Stevens Point Center
,
Weston Center
3501 CRANBERRY BLVD
WESTON, WI 54476
A041701, A Randomized Phase II/III Study of Conventional Chemotherapy +/- Uproleselan (GMI-1271) in Older Adults with Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy
Fagbemi, Seth O
Blood - AML - Acute Myelogenous
Adult
This phase II/III trial studies how well daunorubicin and cytarabine with or without uproleselan works in treating older adult patients with acute myeloid leukemia receiving intensive induction chemotherapy. Drugs used in chemotherapy, such as daunorubicin and cytarabine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Uproleselan may prevent cancer from returning or getting worse. Giving daunorubicin and cytarabine with uproleselan may work better in treating patients with acute myeloid leukemia compared to daunorubicin and cytarabine alone.
Gallagher, Ashley M
(715) 387-7687
Diagnostic & Treatment Center
3401 CRANBERRY BLVD
WESTON, WI 54476
Marshfield Clinic Cancer Care At St Michaels
900 ILLINOIS AVE
STEVENS POINT, WI 54481
Marshfield Clinic Cancer Center - Eau Claire
2200 Craig Road
Eau Claire, WI 54701
Marshfield Medical Center - Rice Lake
1700 W STOUT ST
RICE LAKE, WI 54868
Minocqua Center
9601 TOWNLINE RD
MINOCQUA, WI 54548
MMC - Marshfield
1000 N OAK AVE
MARSHFIELD, WI 54449
Stevens Point Center
,
Wausau Center
2727 PLAZA DRIVE
WAUSAU, WI 54401
Weston Center
3501 CRANBERRY BLVD
WESTON, WI 54476
A081801, Integration of Immunotherapy Into Adjuvant
Therapy for Resected NSCLC: ALCHEMIST Chemo-IO (A
component of the ALCHEMIST trials)
Onitilo, Adedayo A
Lung - Lung
Adult
This phase III ALCHEMIST trial compares the addition of pembrolizumab to usual chemotherapy versus usual chemotherapy for the treatment of stage IB, II, or IIIA non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Drugs used in chemotherapy, such as cisplatin, pemetrexed, carboplatin, gemcitabine hydrochloride, and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. The purpose of this trial is to find out if the addition of pembrolizumab to usual chemotherapy is better or worse than usual chemotherapy alone for non-small cell lung cancer.
Adam, Iddrisu
(715) 389-4041
Chippewa Center
2655 CTY HWY I
CHIPPEWA FALLS, WI 54729
Ladysmith Center
906 College Ave W
Ladysmith, WI 54848
Marshfield Clinic Cancer Center - Eau Claire
2200 Craig Road
Eau Claire, WI 54701
Marshfield Medical Center - Rice Lake
1700 W STOUT ST
RICE LAKE, WI 54868
Minocqua Center
9601 TOWNLINE RD
MINOCQUA, WI 54548
MMC - Marshfield
1000 N OAK AVE
MARSHFIELD, WI 54449
Stevens Point Center
,
Wausau Center
2727 PLAZA DRIVE
WAUSAU, WI 54401
Weston Center
3501 CRANBERRY BLVD
WESTON, WI 54476
Wisconsin Rapids Center
220 24TH ST SOUTH
WISCONSIN RAPIDS, WI 54494
A091802, Phase II Randomized Trial of Avelumab Plus Cetuximab Versus Avelumab Alone in Advanced Cutaneous Squamous Cell Carcinoma of the Skin (cSCC)
Onitilo, Adedayo A
Skin
Adult
This phase II trial studies how well avelumab with or without cetuximab work in treating patients with skin squamous cell cancer that has spread to other places in the body. Immunotherapy with monoclonal antibodies, such as avelumab and cetuximab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.
Baker, Jessica
(715) 344-3048
Diagnostic & Treatment Center
3401 CRANBERRY BLVD
WESTON, WI 54476
Marshfield Clinic Cancer Center - Eau Claire
2200 Craig Road
Eau Claire, WI 54701
Marshfield Medical Center - Rice Lake
1700 W STOUT ST
RICE LAKE, WI 54868
Minocqua Center
9601 TOWNLINE RD
MINOCQUA, WI 54548
MMC - Marshfield
1000 N OAK AVE
MARSHFIELD, WI 54449
Stevens Point Center
,
Wausau Center
2727 PLAZA DRIVE
WAUSAU, WI 54401
Weston Center
3501 CRANBERRY BLVD
WESTON, WI 54476
A151216, Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)
Onitilo, Adedayo A
Lung - Lung
Adult
This research trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.
Adam, Iddrisu
(715) 389-4041
Chippewa Center
2655 CTY HWY I
CHIPPEWA FALLS, WI 54729
Diagnostic & Treatment Center
3401 CRANBERRY BLVD
WESTON, WI 54476
Ladysmith Center
906 College Ave W
Ladysmith, WI 54848
Lakeview Medical Center
1700 West Stout Street
Rice Lake, WI 54868
Marshfield Clinic At James Beck Cancer Center
2251 NORTH SHORE DR
RHINELANDER, WI 54501
Marshfield Clinic Cancer Care At St Michaels
900 ILLINOIS AVE
STEVENS POINT, WI 54481
Marshfield Clinic Cancer Center - Eau Claire
2200 Craig Road
Eau Claire, WI 54701
Marshfield Medical Center
611 Saint Joseph Ave
Marshfield, WI 54449
Marshfield Medical Center - Rice Lake
1700 W STOUT ST
RICE LAKE, WI 54868
Mfld Clinic Cancer Care at Sacred Heart Hospital
900 W CLAIREMONT AVE
EAU CLAIRE, WI 54701
Minocqua Center
9601 TOWNLINE RD
MINOCQUA, WI 54548
MMC - Marshfield
1000 N OAK AVE
MARSHFIELD, WI 54449
Sacred Heart Hospital (Eau Claire)
900 W Clairemont Ave
Eau Claire, WI 54701
St. Mary's
2251 North Shore Drive
Rhinelander, WI 54501
St. Michaels Hospital
900 Illinois Ave
Stevens Point, WI 54481
Wausau Center
2727 PLAZA DRIVE
WAUSAU, WI 54401
Weston Center
3501 CRANBERRY BLVD
WESTON, WI 54476
Wisconsin Rapids Center
220 24TH ST SOUTH
WISCONSIN RAPIDS, WI 54494
A151804, Establishment of a National Biorepository to Advance Studies of Immune-Related Adverse Events
Gokalp Yasar, Demet
Miscellaneous Neoplasm
Adult, Child
This trial collects research data and samples from patients who experience immunotherapy side effects to store for use in future research studies. Studying research data and samples from patients who experience immunotherapy side effects may help researchers better understand how to predict, prevent, and treat these side effects.
Craig, Chani L
(715) 358-1838
Chippewa Center
2655 CTY HWY I
CHIPPEWA FALLS, WI 54729
Diagnostic & Treatment Center
3401 CRANBERRY BLVD
WESTON, WI 54476
Eau Claire Center
2116 Craig Rd
Eau Claire, WI 54701
Ladysmith Center
906 College Ave W
Ladysmith, WI 54848
Marshfield Clinic Cancer Center - Eau Claire
2200 Craig Road
Eau Claire, WI 54701
Marshfield Medical Center - Rice Lake
1700 W STOUT ST
RICE LAKE, WI 54868
Minocqua Center
9601 TOWNLINE RD
MINOCQUA, WI 54548
MMC - Marshfield
1000 N OAK AVE
MARSHFIELD, WI 54449
Stevens Point Center
,
Wausau Center
2727 PLAZA DRIVE
WAUSAU, WI 54401
Weston Center
3501 CRANBERRY BLVD
WESTON, WI 54476
Wisconsin Rapids Center
220 24TH ST SOUTH
WISCONSIN RAPIDS, WI 54494
A171901, Older Non-Small Cell Lung Cancer Patients (>/= 70 Years of Age) Treated With First-Line MK-3475 (Pembrolizumab)+/- Chemotherapy (Oncologists/Patients Choice)
Tanawattanacharoen, P
Lung - Lung
Adult
This trial studies the side effects of pembrolizumab with or without chemotherapy in treating patients with stage IV non-small cell lung cancer that has come back (recurrent) and has spread to other places in the body (advanced). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Drugs used in chemotherapy, such as pemetrexed and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving pembrolizumab with or without chemotherapy may shrink the tumor in older patients with non-small cell lung cancer.
Chippewa Center
2655 CTY HWY I
CHIPPEWA FALLS, WI 54729
Ladysmith Center
906 College Ave W
Ladysmith, WI 54848
Marshfield Clinic Cancer Center - Eau Claire
2200 Craig Road
Eau Claire, WI 54701
Marshfield Medical Center - Rice Lake
1700 W STOUT ST
RICE LAKE, WI 54868
Minocqua Center
9601 TOWNLINE RD
MINOCQUA, WI 54548
MMC - Marshfield
1000 N OAK AVE
MARSHFIELD, WI 54449
Stevens Point Center
,
Wausau Center
2727 PLAZA DRIVE
WAUSAU, WI 54401
Weston Center
3501 CRANBERRY BLVD
WESTON, WI 54476
Wisconsin Rapids Center
220 24TH ST SOUTH
WISCONSIN RAPIDS, WI 54494
AALL1731, A Phase 3 Trial Investigating Blinatumomab ( NSC# 765986) in Combination With Chemotherapy in Patients With Newly Diagnosed Standard Risk or Down Syndrome B-Lymphoblastic Leukemia (B-ALL) and the Treatment of Patients With Localized B-Lymphoblastic Lymphoma (B-LLy)
Manalang, Michelle
Blood - ALL - Acute Lymphoblastic
Lymph Gland - Non-Hodgkin's
Blood - ALL - Acute Lymphocyctic
Child, Adult
This phase III trial studies how well blinatumomab works in combination with chemotherapy in treating patients with or without Down syndrome and newly diagnosed, standard risk B-lymphoblastic leukemia or B-lymphoblastic lymphoma. Monoclonal antibodies, such as blinatumomab, may induce changes in body's immune system and may interfere with the ability of cancer cells to grow and spread. Drugs used in chemotherapy, such as vincristine, dexamethasone, prednisone, prednisolone, pegaspargase, methotrexate, cytarabine, mercaptopurine, doxorubicin, cyclophosphamide, and thioguanine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Leucovorin decreases the toxic effects of methotrexate. Giving monoclonal antibody therapy with chemotherapy may kill more cancer cells. Giving blinatumomab and combination chemotherapy may work better then combination chemotherapy alone in treating patients with B-ALL. This trial also assigns patients into different chemotherapy treatment regimens based on risk (the chance of cancer returning after treatment). Treating patients with chemotherapy based on risk may help doctors decide which patients can best benefit from which chemotherapy treatment regimens.
Welter, Stacy L
(715) 221-6492
MMC - Marshfield
1000 N OAK AVE
MARSHFIELD, WI 54449